Sculerati N, Ledesma-Medina J, Finegold D N, Stool S E
Department of Otolaryngology, New York University Medical Center, NY.
Arch Otolaryngol Head Neck Surg. 1990 Jun;116(6):704-7. doi: 10.1001/archotol.1990.01870060062011.
Twenty-two phenotypic females with Turner syndrome underwent prospective otologic evaluation including a standard history, physical examination, audiogram, and tympanogram. Eight of these patients had computed tomography of the temporal bones. Eighty-two percent of the patients had a history of chronic or recurrent ear infections. Eleven patients (50%) had previous myringotomy and tube placement and 4 (16%) had undergone tympanoplasty or tympanomastoidectomy for sequelae of otitis media. Ten patients (45%) had middle ear effusions evident on examination. Sixteen patients (73%) had hearing loss in at least one ear at the time of examination. Sensorineural losses were evident in 37% of patients. No malformations of the otic capsule were noted on computed tomography. The high prevalence of both hearing loss and otitis media in Turner syndrome warrants otologic and audiologic assessment of patients with this chromosomal anomaly.
22名患有特纳综合征的表型女性接受了前瞻性耳科评估，包括标准病史、体格检查、听力图和鼓室图。其中8名患者进行了颞骨计算机断层扫描。82%的患者有慢性或复发性耳部感染史。11名患者（50%）曾行鼓膜切开置管术，4名患者（16%）因中耳炎后遗症接受了鼓室成形术或鼓室乳突切除术。10名患者（45%）检查时可见中耳积液。16名患者（73%）检查时至少有一只耳朵听力损失。37%的患者有明显的感音神经性听力损失。计算机断层扫描未发现耳囊畸形。特纳综合征中听力损失和中耳炎的高患病率值得对患有这种染色体异常的患者进行耳科和听力学评估。
