Ozanne A E, Krimmer H, Murdoch B E
Department of Speech and Hearing, University of Queensland, St. Lucia, Australia.
Am J Ment Retard. 1990 May;94(6):625-32.
The speech and language skills of 29 children with early treated phenylketonuria (PKU) were reported. The performances of two experimental groups that differed in language development level on standardized speech/language tests were compared with the performances of appropriate control groups matched for age, sex, and socioeconomic level. No significant differences were found on speech and/or language measures between either of the two experimental groups and their respective controls. Examination of individual scores, however, did reveal linguistic impairment in a small number of persons with PKU. No pattern of linguistic deficit was found nor were there any consistent relations between individual speech/language scores, cognitive abilities, or dietary control ratings.
报告了29名早期接受治疗的苯丙酮尿症（PKU）患儿的言语和语言技能。将两个在语言发展水平上存在差异的实验组在标准化言语/语言测试中的表现，与在年龄、性别和社会经济水平上匹配的适当对照组的表现进行了比较。在两个实验组中的任何一组与其各自的对照组之间，在言语和/或语言测量方面均未发现显著差异。然而，对个体分数的检查确实发现少数苯丙酮尿症患者存在语言障碍。未发现语言缺陷模式，个体言语/语言分数、认知能力或饮食控制评分之间也没有任何一致的关系。
