Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.
ChemSusChem. 2013 Mar;6(3):430-2. doi: 10.1002/cssc.201200838. Epub 2013 Feb 11.
Terminal aromatic alkynes are converted rapidly into ketones in a regioselective manner by treatment of their microemulsions with 0.33 M mineral acid between 80 and 140 °C. Internal and aliphatic acetylenes are likewise hydrated, but require longer reaction periods. The products are easily isolated from the reaction mixtures by phase separation. Replacement of H2 O by D2 O leads to the formation of trideuteriomethyl ketones.
终端芳香炔烃在 80 至 140°C 下用 0.33 M 矿物酸处理其微乳液，可以快速以区域选择性方式转化为酮。内部和脂肪族炔烃也同样水合，但需要更长的反应时间。产物可以通过相分离从反应混合物中轻松分离。用 D2O 代替 H2O 会导致形成氘代甲基酮。
