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分娩时表现为黏膜下平滑肌瘤的低级别子宫上皮样血管内皮瘤

Low-Grade Uterine Epithelioid Hemangioendothelioma Presented as a Submucosal Leiomyoma during Labor.

作者信息

Koutsopoulos Anastasios V, Sivridis Efthimios, Tsikouras Panagiotis, Liberis Vasileios, Karpathiou Georgia, Giatromanolaki Alexandra

机构信息

Department of Pathology, Faculty of Medicine, Democritus University of Thrace and University General Hospital of Alexandroupolis, Thrace, 68100 Alexandroupolis, Greece.

出版信息

Case Rep Pathol. 2013;2013:423584. doi: 10.1155/2013/423584. Epub 2013 Jan 20.

DOI:10.1155/2013/423584
PMID:23401828
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3563176/
Abstract

With the exception of leiomyomas, soft tissue tumors of the uterine corpus are not common. This is particularly true for vascular neoplasms, with the epithelioid hemangioendothelioma being a curiosity; not more than twenty-two cases of malignant hemangioendotheliomas have been reported in the literature so far, all of which were high-grade hemangioendotheliomas (hemangiosarcomas). We present herewith a unique case of low-grade epithelioid hemangioendothelioma of the uterus in a pregnant woman aged 29 years. The clinical, histological, and immunohistochemical characteristics of this entity, together with its differential diagnosis, are discussed.

摘要

除平滑肌瘤外,子宫体的软组织肿瘤并不常见。血管性肿瘤尤其如此,上皮样血管内皮瘤是一种罕见病;迄今为止,文献中报道的恶性血管内皮瘤病例不超过22例,所有这些都是高级别血管内皮瘤(血管肉瘤)。我们在此报告一例29岁孕妇的子宫低级别上皮样血管内皮瘤的独特病例。本文讨论了该实体的临床、组织学和免疫组化特征及其鉴别诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbbb/3563176/14e047b83c91/CRIM.PATHOLOGY2013-423584.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbbb/3563176/14e047b83c91/CRIM.PATHOLOGY2013-423584.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbbb/3563176/14e047b83c91/CRIM.PATHOLOGY2013-423584.001.jpg

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本文引用的文献

1
Epithelioid angiosarcoma of the uterus: a review of management.子宫上皮样血管肉瘤:治疗综述
Arch Gynecol Obstet. 2008 Nov;278(5):401-4. doi: 10.1007/s00404-008-0727-z. Epub 2008 Jul 19.
2
Angiosarcoma of the uterus: report of 2 new cases with deviant clinicopathologic features and review of the literature.子宫血管肉瘤:2例具有异常临床病理特征的新病例报告及文献复习
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Uterine sarcomas.子宫肉瘤
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Primary uterine angiosarcoma.原发性子宫血管肉瘤
Gynecol Oncol. 1999 Nov;75(2):272-6. doi: 10.1006/gyno.1999.5566.
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Uterine angiosarcomas: a morphologic and immunohistochemical study of four cases.
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The family of epithelioid vascular tumors.上皮样血管肿瘤家族
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Angiosarcoma of the uterus following radiotherapy for squamous cell carcinoma of the cervix.子宫颈鳞状细胞癌放疗后发生的子宫血管肉瘤。
Eur J Obstet Gynecol Reprod Biol. 1993 May;49(3):193-7. doi: 10.1016/0028-2243(93)90269-i.
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Epithelioid angiosarcoma arising in uterine leiomyomas.子宫平滑肌瘤中发生的上皮样血管肉瘤。
Am J Clin Pathol. 1993 Nov;100(5):514-8. doi: 10.1093/ajcp/100.5.514.
9
Epithelioid angiosarcoma of the uterus arising in a leiomyoma with associated ovarian and tubal angiomatosis.子宫上皮样血管肉瘤发生于伴有卵巢和输卵管血管瘤病的平滑肌瘤中。
Am J Clin Pathol. 1994 Sep;102(3):388-9. doi: 10.1093/ajcp/102.3.388.
10
Angiosarcomas of the uterus and ovary: clinicopathologic report.子宫和卵巢血管肉瘤:临床病理报告。
Cancer. 1982 Apr 1;49(7):1469-75. doi: 10.1002/1097-0142(19820401)49:7<1469::aid-cncr2820490726>3.0.co;2-k.