Burganova G R
Eksp Klin Gastroenterol. 2012(4):91-7.
Liver cirrhosis is a problem that requires new therapeutical approaches because the existing treatment is not effective enough. The most promising at present may be new treatments in the field of regenerative medicine and in particular the use stem cells. Autologous hematopoietic stem cells were injected into the celiac trunk of patients with alcoholic cirrhosis. Liver biopsy specimens were stained immunohistochemically with antibodies against CD 34, alpha-smooth-muscle actin (a-SMA) and Bcl-2. The results showed that this approach is effective in suppression of fibrogenesis in liver and immunohistochemical methods are highly informative in assessing the effectiveness of stem cells transplantation.
肝硬化是一个需要新治疗方法的问题，因为现有的治疗方法不够有效。目前最有前景的可能是再生医学领域的新治疗方法，特别是干细胞的应用。将自体造血干细胞注入酒精性肝硬化患者的腹腔干。肝活检标本用抗CD 34、α平滑肌肌动蛋白（α-SMA）和Bcl-2抗体进行免疫组织化学染色。结果表明，这种方法在抑制肝脏纤维生成方面是有效的，免疫组织化学方法在评估干细胞移植的有效性方面具有很高的信息量。
