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下腔静脉滤器的预防性放置:一则警示

Prophylactic placement of vena caval filters: a cautionary note.

作者信息

Greene B S, Hellwarth G, Rundell W K, Lemmon G W, Procter C D

机构信息

Department of Surgery, USAF Medical Center, Wright-Patterson AFB, Dayton, Ohio 45433.

出版信息

Ann Vasc Surg. 1990 May;4(3):229-32. doi: 10.1007/BF02009449.

Abstract

Greenfield filter placement in patients without deep venous thrombosis has been performed when such patients were felt to be at high risk for asymptomatic deep venous thrombosis and subsequent embolus. In this group placement is termed "truly prophylactic" to differentiate from placement in a patient with documented deep venous thrombosis which has not yet embolized. A retrospective review of Greenfield filter placement at five Dayton, Ohio, community hospitals over three years revealed 59 filters placed in 58 patients. Of these 90% were placed surgically and 10% percutaneously at an average cost of $4,141.00 per surgical procedure. Indications included traditional as well as true prophylaxis. A low morbidity and no mortality related to filter placement was observed. The high efficacy and safety of filter placement seen at large institutions is also found in our community hospital experience despite placement by physicians who perform the procedure infrequently. Although filter placement in patients at a high risk for silent fatal pulmonary emboli may prevent a rare mortality, widespread use of this modality for pulmonary embolus prophylaxis is costly and not without patient risk. We caution against the use of Greenfield filters for pulmonary embolus prophylaxis in patients without deep venous thrombosis until evidence of superior efficacy compared to other forms of prophylaxis can be demonstrated.

摘要

对于那些被认为无症状深静脉血栓形成及随后发生栓子风险较高的非深静脉血栓形成患者,已实施了格林菲尔德滤器置入术。在这组患者中,滤器置入被称为“真正的预防性”,以区别于在已记录有深静脉血栓形成但尚未发生栓塞的患者中进行的滤器置入。对俄亥俄州代顿市五家社区医院三年来格林菲尔德滤器置入情况的回顾性研究显示,58例患者共置入了59个滤器。其中90%通过手术置入,10%经皮置入,每次手术平均费用为4141.00美元。置入指征包括传统指征以及真正的预防性指征。观察到与滤器置入相关的低发病率和无死亡率。尽管置入手术由不常进行该操作的医生实施,但在我们社区医院的经验中也发现了大型机构中所见的滤器置入的高效性和安全性。虽然对有隐匿性致命肺栓塞高风险的患者进行滤器置入可能预防罕见的死亡,但广泛使用这种方式进行肺栓塞预防成本高昂且并非没有患者风险。在能够证明其疗效优于其他预防形式之前,我们告诫不要对非深静脉血栓形成患者使用格林菲尔德滤器进行肺栓塞预防。

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