Health Outcomes Practice, Kantar Health, 11 Madison Avenue, 12th Floor, New York, NY, USA.
Expert Rev Pharmacoecon Outcomes Res. 2013 Feb;13(1):131-9. doi: 10.1586/erp.12.82.
To assess the costs associated with sleep symptoms among patients with fibromyalgia (FM).
PATIENTS & METHODS: Patients reporting physician-diagnosed FM from the National Health and Wellness Survey were categorized into three groups based on the number of sleep symptoms reported: two or more sleep symptoms (n = 1353), one sleep symptom (n = 574) and no sleep symptoms (n = 269). Annual direct and indirect costs were compared among the groups controlling for relevant confounders.
After adjusting for demographic and health characteristics, patients with FM with one, two or more sleep symptoms had higher annual physician costs (US$12,328 and US$12,261, respectively) and higher annual emergency room visit costs (US$846 and US$729, respectively) than patients with FM without any sleep symptoms (physician visit costs: US$9845; emergency room visit costs: US$527; all p < 0.05). Similarly, both patients with one (US$18,100) and two or more sleep symptoms (US$18,428) reported higher total indirect costs compared with those without any sleep symptoms (US$14,711; p < 0.05).
Among the FM population, sleep symptoms were prevalent and associated with higher direct and indirect costs, suggesting improved management may have long-term cost savings.
评估纤维肌痛 (FM) 患者睡眠症状相关的成本。
从全国健康与健康调查中报告有医生诊断的 FM 的患者，根据报告的睡眠症状数量分为三组：两个或更多睡眠症状（n = 1353）、一个睡眠症状（n = 574）和无睡眠症状（n = 269）。在控制相关混杂因素的情况下，比较了各组的年度直接和间接成本。
在调整人口统计学和健康特征后，有一个、两个或更多睡眠症状的 FM 患者的年度医生费用（分别为 12328 美元和 12261 美元）和年度急诊就诊费用（分别为 846 美元和 729 美元）均高于没有任何睡眠症状的 FM 患者（医生就诊费用：9845 美元；急诊就诊费用：527 美元；均 p < 0.05）。同样，有一个（18100 美元）和两个或更多睡眠症状（18428 美元）的患者报告的总间接成本均高于没有任何睡眠症状的患者（14711 美元；均 p < 0.05）。
在 FM 人群中，睡眠症状很常见，且与更高的直接和间接成本相关，这表明改善管理可能具有长期成本节约。
