生物合成工程化的B28(K)-B29(P)人胰岛素单体在水和水/乙腈溶液中的结构。 - Suppr

Biosynthetic engineered B28(K)-B29(P) human insulin monomer structure in water and in water/acetonitrile solutions.

作者信息

Borowicz Piotr, Bocian Wojciech, Sitkowski Jerzy, Bednarek Elżbieta, Mikiewicz-Syguła Diana, Kurzynoga Dariusz, Stadnik Dorota, Surmacz-Chwedoruk Weronika, Koźmiński Wiktor, Kozerski Lech

机构信息

Institute of Biotechnology and Antibiotics, Warsaw, Poland.

出版信息

J Biomol NMR. 2013 Mar;55(3):303-9. doi: 10.1007/s10858-013-9713-2. Epub 2013 Feb 13.

DOI:10.1007/s10858-013-9713-2

PMID:23404086

Abstract

摘要

相似文献

Biosynthetic engineered B28(K)-B29(P) human insulin monomer structure in water and in water/acetonitrile solutions.生物合成工程化的B28(K)-B29(P)人胰岛素单体在水和水/乙腈溶液中的结构。

J Biomol NMR. 2013 Mar;55(3):303-9. doi: 10.1007/s10858-013-9713-2. Epub 2013 Feb 13.

Novel recombinant insulin analogue with flexible C-terminus in B chain. NMR structure of biosynthetic engineered A22G-B31K-B32R human insulin monomer in water/acetonitrile solution.新型重组胰岛素类似物，B 链末端具有柔性 C 端。水/乙腈溶液中生物合成工程化 A22G-B31K-B32R 人胰岛素单体的 NMR 结构。

Int J Biol Macromol. 2011 Nov 1;49(4):548-54. doi: 10.1016/j.ijbiomac.2011.06.008. Epub 2011 Jun 16.

NMR structure of biosynthetic engineered human insulin monomer B31(Lys)-B32(Arg) in water/acetonitrile solution. Comparison with the solution structure of native human insulin monomer.生物合成工程化人胰岛素单体B31（赖氨酸）-B32（精氨酸）在水/乙腈溶液中的核磁共振结构。与天然人胰岛素单体溶液结构的比较。

Biopolymers. 2008 Oct;89(10):820-30. doi: 10.1002/bip.21018.

Structure of human insulin monomer in water/acetonitrile solution.人胰岛素单体在水/乙腈溶液中的结构。

J Biomol NMR. 2008 Jan;40(1):55-64. doi: 10.1007/s10858-007-9206-2. Epub 2007 Nov 27.

[Solid state isotope hydrogen exchange for deuterium and tritium in human gene-engineered insulin].[人基因工程胰岛素中氘和氚的固态同位素氢交换]

Bioorg Khim. 2014 Jan-Feb;40(1):31-41. doi: 10.1134/s1068162014010154.

On the origin of the hydrogen-bond-network nature of water: X-ray absorption and emission spectra of water-acetonitrile mixtures.论水的氢键网络性质的起源：水 - 乙腈混合物的X射线吸收和发射光谱

Angew Chem Int Ed Engl. 2011 Nov 4;50(45):10621-5. doi: 10.1002/anie.201104161. Epub 2011 Sep 14.

Monte Carlo simulations of the solution structure of simple alcohols in water-acetonitrile mixtures.水-乙腈混合物中简单醇类溶液结构的蒙特卡罗模拟。

J Phys Chem B. 2005 Mar 31;109(12):5855-72. doi: 10.1021/jp045570q.

Competing non-covalent interactions in alkali metal ion-acetonitrile-water clusters.碱金属离子-乙腈-水团簇中的竞争非共价相互作用。

J Phys Chem A. 2005 May 5;109(17):3880-6. doi: 10.1021/jp050534s.

Study of the preferential solvation of some betaine dyes in binary solvent mixtures.二元溶剂混合物中某些甜菜碱染料优先溶剂化的研究。

Spectrochim Acta A Mol Biomol Spectrosc. 2001 Aug;57(9):1877-84. doi: 10.1016/s1386-1425(01)00418-8.

Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues.苯酚和间甲酚在胰岛素六聚体中的相互作用及其对B28脯氨酸→天冬氨酸胰岛素类似物缔合特性的影响。

Biochemistry. 1998 Aug 18;37(33):11516-23. doi: 10.1021/bi980807s.

引用本文的文献

Insight into human insulin aggregation revisited using NMR derived translational diffusion parameters.利用核磁共振衍生的平移扩散参数重新审视人类胰岛素聚集情况。

J Biomol NMR. 2018 Jun;71(2):101-114. doi: 10.1007/s10858-018-0197-y. Epub 2018 Jun 12.

本文引用的文献

Recombinant A22(G)-B31 (R)-human insulin. A22 addition introduces conformational mobility in B chain C-terminus.重组A22(G)-B31 (R)-人胰岛素。添加A22会在B链C末端引入构象灵活性。

J Biomol NMR. 2012 Apr;52(4):365-70. doi: 10.1007/s10858-012-9612-y. Epub 2012 Feb 14.

Int J Biol Macromol. 2011 Nov 1;49(4):548-54. doi: 10.1016/j.ijbiomac.2011.06.008. Epub 2011 Jun 16.

Direct insight into insulin aggregation by 2D NMR complemented by PFGSE NMR.通过二维核磁共振（2D NMR）并辅以脉冲场梯度自旋回波核磁共振（PFGSE NMR）直接洞察胰岛素聚集情况。

Proteins. 2008 May 15;71(3):1057-65. doi: 10.1002/prot.21969.

Structure of human insulin monomer in water/acetonitrile solution.人胰岛素单体在水/乙腈溶液中的结构。

J Biomol NMR. 2008 Jan;40(1):55-64. doi: 10.1007/s10858-007-9206-2. Epub 2007 Nov 27.

Kinetics of different processes in human insulin amyloid formation.人胰岛素淀粉样蛋白形成过程中不同进程的动力学

J Mol Biol. 2007 Feb 9;366(1):258-74. doi: 10.1016/j.jmb.2006.11.008. Epub 2006 Nov 9.

Thermal dissociation and unfolding of insulin.胰岛素的热解离与去折叠

Biochemistry. 2005 Aug 23;44(33):11171-7. doi: 10.1021/bi0507940.

Ethanol-perturbed amyloidogenic self-assembly of insulin: looking for origins of amyloid strains.乙醇干扰胰岛素的淀粉样蛋白生成自组装：探寻淀粉样蛋白菌株的起源。

Biochemistry. 2005 Jun 28;44(25):8948-58. doi: 10.1021/bi050281t.

Engineering predictability and protraction in a basal insulin analogue: the pharmacology of insulin detemir.基础胰岛素类似物中工程化的可预测性和延长作用：地特胰岛素的药理学

Int J Obes Relat Metab Disord. 2004 Sep;28 Suppl 2:S23-8. doi: 10.1038/sj.ijo.0802746.

Mechanism of insulin fibrillation: the structure of insulin under amyloidogenic conditions resembles a protein-folding intermediate.胰岛素纤维化机制：在淀粉样蛋白生成条件下胰岛素的结构类似于蛋白质折叠中间体。

J Biol Chem. 2004 May 14;279(20):21449-60. doi: 10.1074/jbc.M314141200. Epub 2004 Feb 26.

The structure of T6 human insulin at 1.0 A resolution.分辨率为1.0埃的T6人胰岛素结构。

Acta Crystallogr D Biol Crystallogr. 2003 Mar;59(Pt 3):474-82. doi: 10.1107/s0907444902023685. Epub 2003 Feb 21.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验

Biosynthetic engineered B28(K)-B29(P) human insulin monomer structure in water and in water/acetonitrile solutions.

作者信息

机构信息

出版信息

相似文献

引用本文的文献

本文引用的文献

文献AI研究员

用中文搜PubMed

文档翻译

Suppr 超能文献

相似文献

引用本文的文献

本文引用的文献