Ghaziuddin M, Ghaziuddin N, Stein G S
University of Michigan Hospitals, Ann Arbor 48109-0706.
Can J Psychiatry. 1990 Apr;35(3):239-42. doi: 10.1177/070674379003500307.
In a study of the prevalence of life events in recurrent depression, 40 patients with recurrent episodes were compared to 33 who were experiencing their first depressive illness. Thirty out of 33 (90.9%) first episode cases experienced life events prior to the onset of illness whereas only 20 out of 40 (50%) of the recurrent group gave such as history. Patients with a first episode had an average of 2.2 life events in the six months prior to onset, whereas recurrent patients experienced average of only 0.8 life events (p less than 0.05). Negative as well as exit events were also significantly more frequent among the first episode group. Although life events, age and sex all contributed to the recurrence of depression, most of the variance was not accounted for by any of these factors.
在一项关于复发性抑郁症中生活事件发生率的研究中，将40例复发性发作的患者与33例首次患抑郁症的患者进行了比较。33例首次发作病例中有30例（90.9%）在发病前经历了生活事件，而复发组的40例中只有20例（50%）有此类病史。首次发作的患者在发病前六个月平均有2.2次生活事件，而复发患者平均只有0.8次生活事件（p小于0.05）。首次发作组中负面事件和丧失事件也明显更为频繁。尽管生活事件、年龄和性别都与抑郁症的复发有关，但这些因素都不能解释大部分的差异。
