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恶性疟原虫感染所致手足搐搦

Tetany with Plasmodium falciparum infection.

作者信息

Singh P S, Singh Neha

机构信息

UP RIMS and R Medical College, Saifai, Etawah 206301, Uttar Pradesh.

出版信息

J Assoc Physicians India. 2012 Jul;60:57-8.

PMID:23405546
Abstract

Plasmodium falciparum is a malarial infection with high morbidity and wide spectrum of atypical presentation. Here we report an unusual presentation of malaria as tetany with alteration in calcium,phosphate and magnesium metabolism Hypocalcaemia in malaria can cause prolonged Q-Tc interval which could be arisk factor for quinine cardiotoxicity and sudden death Hence monitoring of serum calcium in severe malarial infection and cautious use of quinine in such patients is very important in management

摘要

恶性疟原虫是一种发病率高且有广泛非典型表现的疟疾感染。在此,我们报告一例不寻常的疟疾表现,即手足搐搦伴钙、磷和镁代谢改变。疟疾中的低钙血症可导致Q-Tc间期延长,这可能是奎宁心脏毒性和猝死的危险因素。因此,在严重疟疾感染中监测血清钙水平,并在此类患者中谨慎使用奎宁,对治疗非常重要。

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