Vig K W
Department of Orthodontics and Pediatric Dentistry, University of Michigan School of Dentistry, Ann Arbor 48109-1078.
Cleft Palate J. 1990 Apr;27(2):141-5. doi: 10.1597/1545-1569(1990)027<0141:ocatcd>2.3.co;2.
The contemporary management of patients with craniofacial anomalies involves a team approach of multiple specialists. Interaction between the basic scientist, developmental biologist, and the clinician should be an important aspect of interdisciplinary research if clinically relevant questions are to be addressed under rigorous laboratory conditions. The clinical investigator may be unfamiliar with the terminology and methodology of basic biomedical research. As a result, there can be a lack of communication between the clinician and the basic scientist. The role of the orthodontist in a multidisciplinary craniofacial team has evolved largely from an interest in dysmorphology as applied to craniofacial growth and development. The predictability of orthognathic surgery has been derived from the close collaboration between the orthodontist and surgeon and may be applied to the more comprehensive management of patients with craniofacial anomalies. To determine the mechanisms underlying the pathogenesis and response to treatment will require a collaborative approach by the clinician and research scientist to elucidate causal and putative risk factors in the complex genetic and environmental associations involved in craniofacial anomalies.
颅面畸形患者的当代治疗需要多学科专家团队协作。如果要在严格的实验室条件下解决临床相关问题，基础科学家、发育生物学家和临床医生之间的互动应成为跨学科研究的重要方面。临床研究人员可能不熟悉基础生物医学研究的术语和方法。因此，临床医生和基础科学家之间可能缺乏沟通。正畸医生在多学科颅面团队中的作用很大程度上源于对应用于颅面生长发育的畸形学的兴趣。正颌外科手术的可预测性源于正畸医生和外科医生之间的密切合作，并且可应用于颅面畸形患者更全面的治疗。要确定发病机制和对治疗反应的潜在机制，临床医生和研究科学家需要采取协作方法，以阐明颅面畸形所涉及的复杂遗传和环境关联中的因果和假定风险因素。
