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棕榈油和棕榈酸:心血管影响和致癌性的综述。

Palm oil and palmitic acid: a review on cardiovascular effects and carcinogenicity.

机构信息

Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Via Giuseppe La Masa 19, 20156 Milano, Italy.

出版信息

Int J Food Sci Nutr. 2013 Aug;64(5):648-59. doi: 10.3109/09637486.2013.768213. Epub 2013 Feb 14.

Abstract

We reviewed the scientific literature on the evidence of the relationship between palm oil and adverse effects on human health. Few studies have investigated the effects of palm oil per se, and the main reason why it has been associated with negative health effects is the relatively high content of saturated fatty acids (SFAs), particularly palmitic acid, which in turn have been associated with increased risk of coronary heart disease and some tumours. However, more recent investigations on the topic seem to have reconsidered the negative role of the dietary SFAs as a risk factor for cardiovascular diseases and show that not only the type of fat, but also that the triglyceride structure plays a role in cholesterolaemia. As regards to a role in cancer, specific studies on dietary palmitic acid or palm oil and the risk of cancer development are scanty, and the evidence is not convincing.

摘要

我们回顾了有关棕榈油与人类健康不良影响之间关系的科学文献。很少有研究调查过棕榈油本身的影响,而它与负面健康影响相关联的主要原因是其饱和脂肪酸(SFAs)含量相对较高,特别是棕榈酸,这反过来又与冠心病和某些肿瘤的风险增加有关。然而,关于这个主题的最新研究似乎重新考虑了饮食 SFAs 作为心血管疾病风险因素的负面作用,并表明不仅脂肪的类型,而且甘油三酯的结构在胆固醇血症中也起着作用。至于在癌症中的作用,关于饮食棕榈酸或棕榈油与癌症发展风险的具体研究很少,证据也不足为信。

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