Pediatric Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Expert Rev Anticancer Ther. 2013 Feb;13(2):225-36. doi: 10.1586/era.12.180.
Pediatric fibroblastic-myofibroblastic tumors of intermediate prognosis are locally aggressive tumors that rarely metastasize. They are potentially curable, but managing them is often a challenge in terms of their correct diagnosis and appropriate treatment. This paper reviews the most recent biological findings and latest novelties in the multidisciplinary treatment of childhood desmoid-type fibromatoses, infantile fibrosarcoma and inflammatory myofibroblastic tumor.
儿科纤维母细胞-肌纤维母细胞瘤为预后中等的局部侵袭性肿瘤，很少发生转移。其具有潜在的可治愈性，但在正确诊断和适当治疗方面，往往具有挑战性。本文回顾了幼年型硬纤维瘤病、婴儿型纤维肉瘤和炎性肌纤维母细胞瘤的最新生物学研究发现和多学科治疗的最新进展。
