Bolgiano C S, Subramaniam P T, Montanari J M, Minick L
Crit Care Nurse. 1990 May;10(5):47-57.
The use of invasive lines with heparinized fluid for hemodynamic monitoring is a routine procedure in critical care areas. The main objective of this study was to compare the duration of patency of indwelling arterial catheter lines and patient coagulation values when the recommended dilution of 1.0 U heparin/mL was used versus the use of only 0.25 U heparin/mL. One hundred four intensive care unit (ICU) patients were studied. There were no significant differences between the two groups in patency or coagulation values. The results of the study demonstrated that 0.25 U heparin/mL was sufficient to maintain arterial line patency for patients with lines in place for up to 3 days.
在重症监护区域，使用含肝素化液体的侵入性导管进行血流动力学监测是一项常规操作。本研究的主要目的是比较当使用推荐的每毫升1.0单位肝素稀释液与仅使用每毫升0.25单位肝素稀释液时，留置动脉导管的通畅持续时间和患者凝血值。对104名重症监护病房（ICU）患者进行了研究。两组在通畅性或凝血值方面没有显著差异。研究结果表明，对于留置导管长达3天的患者，每毫升0.25单位肝素足以维持动脉导管通畅。
