Mahmood Feroze, Warraich Haider J, Gorman Joseph H, Gorman Robert C, Chen Tzong-Huei, Panzica Peter, Maslow Andrew, Khabbaz Kamal
Department of Anesthesia, Division of Cardiac Surgery, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA.
J Heart Valve Dis. 2012 Nov;21(6):696-701.
Intraoperative real-time three-dimensional transesophageal echocardiography (RT-3D TEE) was used to examine the geometric changes that occur in the mitral annulus immediately after aortic valve replacement (AVR).
A total of 35 patients undergoing elective surgical AVR under cardiopulmonary bypass was enrolled in the study. Intraoperative RT-3D TEE was used prospectively to acquire volumetric echocardiographic datasets immediately before and after AVR. The 3D echocardiographic data were analyzed offline using TomTec Mitral Valve Assessment software to assess changes in specific mitral annular geometric parameters.
Datasets were successfully acquired and analyzed for all patients. A significant reduction was noted in the mitral annular area (-16.3%, p < 0.001), circumference (-8.9%, p < 0.001) and the anteroposterior (-6.3%, p = 0.019) and anterolateral-posteromedial (-10.5%, p < 0.001) diameters. A greater reduction was noted in the anterior annulus length compared to the posterior annulus length (10.5% versus 6.2%, p < 0.05) after AVR. No significant change was seen in the non-planarity angle, coaptation depth, and closure line length. During the period of data acquisition before and after AVR, no significant change was noted in the central venous pressure or left ventricular end-diastolic diameter.
The mitral annulus undergoes significant geometric changes immediately after AVR. Notably, a 16.3% reduction was observed in the mitral annular area. The anterior annulus underwent a greater reduction in length compared to the posterior annulus, which suggested the existence of a mechanical compression by the prosthetic valve.
采用术中实时三维经食管超声心动图(RT - 3D TEE)检查主动脉瓣置换术(AVR)后二尖瓣环立即发生的几何形态变化。
本研究共纳入35例在体外循环下行择期外科AVR的患者。术中前瞻性地使用RT - 3D TEE在AVR前后即刻获取容积超声心动图数据集。使用TomTec二尖瓣评估软件对三维超声心动图数据进行离线分析,以评估特定二尖瓣环几何参数的变化。
所有患者均成功获取并分析了数据集。二尖瓣环面积(-16.3%,p < 0.001)、周长(-8.9%,p < 0.001)以及前后径(-6.3%,p = 0.019)和前外侧 - 后内侧径(-10.5%,p < 0.001)均显著减小。AVR后,前瓣环长度较后瓣环长度减小更明显(10.5%对6.2%,p < 0.05)。非平面角、瓣叶对合深度和闭合线长度未见显著变化。在AVR前后的数据采集期间,中心静脉压和左心室舒张末期直径未见显著变化。
AVR后二尖瓣环立即发生显著的几何形态变化。值得注意的是,二尖瓣环面积减小了16.3%。与后瓣环相比,前瓣环长度减小更明显,提示人工瓣膜存在机械压迫。