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联合肝脏分隔和门静脉结扎的分期肝切除术(ALPPS):肝脏切除术中的一种新方法。

Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS): a new approach in liver resections.

作者信息

Torres Orlando Jorge Martins, Moraes-Junior José Maria Assunção, Lima e Lima Nádia Caroline, Moraes Anmara Moura

机构信息

Department of Digestive Surgery, UDI Hospital, São Luis, MA, Brazil.

出版信息

Arq Bras Cir Dig. 2012 Oct-Dec;25(4):290-2. doi: 10.1590/s0102-67202012000400015.

Abstract

BACKGROUND

Postoperative liver failure consequent to insufficiency of remnant liver is a feared complication in patients who underwent extensive liver resections. The associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) is a new approach for patient which tumor is previously considered unresectable.

AIM

To present ALPPS as an innovative surgical technique of two-staged hepatectomy for the treatment of patients with marginally resectable or initially nonresectable primary and metastatic liver tumors.

TECHNIQUE

The procedure is performed in two steps. The first consists on ligation of the right portal vein branch. Subsequently, total or nearly total parenchyma dissection along the falciform ligament is performed, including the middle hepatic vein. A plastic bag is used to cover the right extended lobe, and the abdomen is drained and closed. The second one is performed after a computer tomography, six to 12 days interval. After laparotomy, the plastic bag is removed. The right artery, right bile duct and the right hepatic vein are divided. The extended right lobe is removed. Drain is placed at the resection surface, and the abdomen is closed.

CONCLUSION

The associating of liver partition and portal vein ligation can enable curative resection of liver metastasis in patients with lesions previously considered unresectable.

摘要

背景

在接受广泛肝切除的患者中,残余肝不足导致的术后肝衰竭是一种可怕的并发症。联合肝脏分隔和门静脉结扎分期肝切除术(ALPPS)是一种针对先前被认为无法切除肿瘤的患者的新方法。

目的

介绍ALPPS作为一种创新的两阶段肝切除手术技术,用于治疗边缘可切除或最初不可切除的原发性和转移性肝肿瘤患者。

技术

该手术分两步进行。第一步是结扎右门静脉分支。随后,沿镰状韧带进行全层或几乎全层实质分离,包括肝中静脉。用一个塑料袋覆盖右扩展叶,然后引流并关闭腹腔。第二步在计算机断层扫描后6至12天进行。剖腹术后,取出塑料袋。切断右动脉、右胆管和右肝静脉。切除扩展的右叶。在切除表面放置引流管,然后关闭腹腔。

结论

联合肝脏分隔和门静脉结扎能够使先前被认为无法切除的肝转移瘤患者实现根治性切除。

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