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灼口综合征与更年期

Burning mouth syndrome and menopause.

作者信息

Dahiya Parveen, Kamal Reet, Kumar Mukesh, Gupta Rajan, Chaudhary Karun

机构信息

Department of Periodontics and Implantology, HIDS, Paonta Sahib, Himachal Pradesh, India.

出版信息

Int J Prev Med. 2013 Jan;4(1):15-20.

Abstract

Menopause is a physiological process typically occurring in the fifth decade of life. One of the most annoying oral symptoms in this age group is the burning mouth syndrome (BMS), which may be defined as an intraoral burning sensation occurring in the absence of identifiable oral lesion or laboratory findings. Pain in burning mouth syndrome may be described as burning, tender, tingling, hot, scalding, and numb sensation in the oral mucosa. Multiple oral sites may be involved, but the anterior two-third part and the tip of tongue are most commonly affected site. There is no definite etiology for BMS other than the precipitating causative factors, and it is still considered idiopathic. Various treatment options like use of benzodiazepine, anti-depressants, analgesics, capsaicin, alpha lipoic acids, and cognitive behavioral therapy are found to be effective, but definite treatment is still unknown. The present article discusses some of the recent concepts of etiopathogenesis of BMS as well as the role of pharmacotherapeutic management in this disorder.

摘要

更年期是一种通常发生在人生第五个十年的生理过程。这个年龄组最恼人的口腔症状之一是灼口综合征(BMS),它可被定义为在没有可识别的口腔病变或实验室检查结果的情况下出现的口腔内烧灼感。灼口综合征的疼痛可描述为口腔黏膜的灼烧感、触痛、刺痛、热感、烫伤感和麻木感。多个口腔部位可能受累,但口腔前三分之二部分和舌尖是最常受影响的部位。除了诱发因素外,BMS没有明确的病因,它仍被认为是特发性的。发现使用苯二氮卓类药物、抗抑郁药、镇痛药、辣椒素、α-硫辛酸以及认知行为疗法等各种治疗选择是有效的,但确切的治疗方法仍然未知。本文讨论了灼口综合征发病机制的一些最新概念以及药物治疗在该疾病中的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c1bb/3570906/8747b95c3444/IJPVM-4-15-g001.jpg

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