School of Pharmacy, University of Wolverhampton, UK.
Old Age Psychiatry, Birmingham and Solihull Mental Health NHS Foundation Trust, Birmingham, UK.
Dent Med Probl. 2020 Jul-Sep;57(3):295-304. doi: 10.17219/dmp/120991.
Burning mouth syndrome (BMS) is idiopathic chronic oral pain, associated with depression, anxiety and pain symptoms. The BMS symptoms include a burning sensation in the tongue and/or other oral mucosa with no underlying medical or dental reasons. As many BMS patients suffer from psychiatric comorbidities, several psychotropic drugs are included in the management of BMS, reducing the complaint, while managing anxiety, depression and pain disorders. In this review, a search of the published literature regarding the management of BMS was conducted. We discuss the BMS etiology, clinically associated symptoms and available treatment options. The current evidence supports some BMS interventions, including alpha-lipoic acid (ALA), clonazepam, capsaicin, and low-level laser therapy (LLLT); however, there is a lack of robust scientific evidence, and large-scale clinical trials with long follow-up periods are needed to establish the role of these BMS management options. This knowledge could raise the awareness of dentists, psychiatrists and general practitioners about these challenges and the available kinds of treatment to improve multidisciplinary management for better health outcomes.
灼口综合征（BMS）是一种特发性慢性口腔疼痛，与抑郁、焦虑和疼痛症状有关。BMS 的症状包括舌部和/或其他口腔黏膜烧灼感，无潜在的医学或牙科原因。由于许多 BMS 患者患有精神共病，因此几种精神药物被纳入 BMS 的治疗中，以减轻疼痛，同时治疗焦虑、抑郁和疼痛障碍。在这篇综述中，我们对已发表的关于 BMS 管理的文献进行了检索。我们讨论了 BMS 的病因、临床相关症状和可用的治疗选择。目前的证据支持一些 BMS 干预措施，包括α-硫辛酸（ALA）、氯硝西泮、辣椒素和低水平激光治疗（LLLT）；然而，缺乏强有力的科学证据，需要进行大规模的临床试验并进行长期随访，以确定这些 BMS 管理选择的作用。这些知识可以提高牙医、精神科医生和全科医生对这些挑战的认识，以及可用的治疗方法，以改善多学科管理，从而获得更好的健康结果。
