来自蜡梅的两种新香豆素苷。

Two new coumarin glycosides from Chimonanthus nitens.

作者信息

Li Qi-Ji, Wang Ming-Li, Yang Xiao-Sheng, Ma Lin, Hao Xiao-Jiang

机构信息

The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang 550002, China.

出版信息

J Asian Nat Prod Res. 2013;15(3):270-5. doi: 10.1080/10286020.2012.762766. Epub 2013 Feb 19.

DOI:10.1080/10286020.2012.762766

PMID:23421779

Abstract

Two new coumarin glycosides, namely nitensosides A-B (1-2), together with six known compounds, scopolin (3), 5,6,7-trimethoxycoumarin (4), d-calycanthine (5), calycanthoside (6), xeroboside (7), and scopoletin (8), were isolated from Chimonanthus nitens. The structures of the new compounds were elucidated by comprehensive analysis of IR, MS, and NMR spectroscopic data. Compounds 3, 4, 7, and 8 showed moderate inhibitory activity against Micrococcus luteus.

摘要

从蜡梅中分离得到两个新的香豆素苷，即亮叶蜡梅苷A - B（1 - 2），以及六个已知化合物，七叶树苷（3）、5,6,7 - 三甲氧基香豆素（4）、右旋卡巴碱（5）、蜡梅苷（6）、沙棘苷（7）和东莨菪素（8）。通过对红外光谱、质谱和核磁共振光谱数据的综合分析确定了新化合物的结构。化合物3、4、7和8对藤黄微球菌显示出中等抑制活性。