Laboratory of Pharmacognosy and Phytochemistry, Faculty of Pharmaceutical Sciences, Ghent University, B-9000 Ghent, Belgium.
J Nat Prod. 2010 Sep 24;73(9):1573-7. doi: 10.1021/np100220g.
The aqueous methanolic leaf extract of Fargesia robusta var. Pingwu was evaluated in vitro for its antioxidant capacity using the TEAC and ORAC assays. C-Glycosyl flavones, farobin A (1) and farobin B (2), together with three known compounds, tricin-5-O-glucopyranoside (3), 2''-O-α-rhamnosyl-6-C-(6-deoxy-ribo-hexos-3-ulosyl)luteolin (4), and luteolin-6-C-glucopyranoside (homoorientin) (5), were isolated from the hydroalcoholic extract of the leaves of F. robusta. The structures of the compounds were determined by spectroscopic analyses including UV, 1D and 2D NMR, and MS. Compounds 1, 4, and 5 exhibited potent antioxidant activity in the TEAC assay, while compounds 1, 3, and 5 showed the highest antioxidant capacity in the ORAC assay.
采用 TEAC 和 ORAC 法评价粗毛箭竹叶片的水甲醇提取物的抗氧化能力。从粗毛箭竹叶片的水醇提取物中分离得到了 C-糖苷黄酮类化合物，罗布麻甲素（1）和罗布麻乙素（2），以及三种已知化合物，三嗪-5-O-吡喃葡萄糖苷（3）、2''-O-α-鼠李糖苷-6-C-（6-去氧-核糖-己三糖-3-基）芦丁（4）和芦丁-6-C-吡喃葡萄糖苷（异荭草苷）（5）。通过包括 UV、1D 和 2D NMR 和 MS 在内的光谱分析确定了化合物的结构。化合物 1、4 和 5 在 TEAC 测定中表现出很强的抗氧化活性，而化合物 1、3 和 5 在 ORAC 测定中表现出最高的抗氧化能力。
