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将卡介苗注入孤立肾肾盂用于治疗移行细胞癌。

Instillation of bacillus Calmette-Guerin into the renal pelvis of a solitary kidney for the treatment of transitional cell carcinoma.

作者信息

Ramsey J C, Soloway M S

机构信息

Department of Urology, University of Tennessee, Memphis.

出版信息

J Urol. 1990 Jun;143(6):1220-2. doi: 10.1016/s0022-5347(17)40230-8.

Abstract

Intravesical bacillus Calmette-Guerin is effective in the treatment and prophylaxis of superficial urothelial cancer of the bladder. There have been few reports of its efficacy and toxicity when instilled into the upper urinary tract. We elected to use intracavitary bacillus Calmette-Guerin in a patient with recurrent high grade transitional cell carcinoma in the renal pelvis of a solitary autotransplanted kidney. The patient required hospitalization and triple-drug therapy after 5 instillations. She was free of tumor 1 year after bacillus Calmette-Guerin instillations.

摘要

膀胱内灌注卡介苗对浅表性膀胱尿路上皮癌的治疗和预防有效。关于其灌注至上尿路时的疗效和毒性,报道较少。我们选择对一名孤立自体移植肾肾盂复发性高级别移行细胞癌患者进行腔内灌注卡介苗。该患者在5次灌注后需要住院并接受三联药物治疗。卡介苗灌注后1年,她未出现肿瘤。

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