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儿童器质性复发性腹痛的警示信号:对100名受试者的研究

Red flags of organic recurrent abdominal pain in children: study on 100 subjects.

作者信息

Motamed Farzaneh, Mohsenipour Reihaneh, Seifirad Soroush, Yusefi Azizolah, Farahmand Fatemeh, Khodadad Ahmad, Falahi Gholamhosein, Najafi Mehri

机构信息

Department of Pediatrics, Tehran University of Medical Sciences, Tehran, Iran ; Growth and Development Research Center, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Iran J Pediatr. 2012 Dec;22(4):457-62.

PMID:23429658
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3533144/
Abstract

OBJECTIVE

A variety of sign, symptoms and laboratory findings are more common in children with organic abdominal pains. This study was performed to evaluate the prevalence of organic and functional abdominal pains and relation of red flags to organic pains in 100 children with recurrent abdominal pain (RAP).

METHODS

One hundred consecutive patients with RAP were enrolled in the study. A complete interview and physical examination was made for each patient, accompanied by a series of laboratory, clinical and para-clinical examinations. The data were recorded and analyzed. Logistic regression analysis was used to model and formulize correlations between sign, symptoms, and laboratory findings with organic and functional abdominal pain.

FINDINGS

Among 100 patients (52% male, 48% female, Age: 9.29±3.17) diagnostic works up revealed organic pain for 57 patients. The most common symptoms of the patients included constipation, diarrhea, chest pain, cough, headache, vomiting, hematuria, and dysuria. Fecal incontinence, delayed puberty, organomegaly, jaundice, and family history of inflammatory bowel disease were reported in none of the patients with RAP. Fever, pain not located in periumbilical area, nocturnal pain, elevated erythrocyte sedimentation rate, weight loss, growth disorder, and abdominal tenderness were among the red flags which revealed diagnosis of organic pain in this study.

CONCLUSION

A series of red flags could increase likelihood of finding organic pain in children with RAP.

摘要

目的

各种体征、症状和实验室检查结果在患有器质性腹痛的儿童中更为常见。本研究旨在评估100例复发性腹痛(RAP)患儿中器质性和功能性腹痛的患病率,以及警示信号与器质性腹痛的关系。

方法

连续纳入100例RAP患儿进行研究。对每位患儿进行全面的访谈和体格检查,并进行一系列实验室、临床和辅助临床检查。记录并分析数据。采用逻辑回归分析对体征、症状和实验室检查结果与器质性和功能性腹痛之间的相关性进行建模和公式化。

结果

在100例患儿(52%为男性,48%为女性,年龄:9.29±3.17岁)中,诊断检查发现57例患儿患有器质性腹痛。患儿最常见的症状包括便秘、腹泻、胸痛、咳嗽、头痛、呕吐、血尿和排尿困难。在所有RAP患儿中均未报告大便失禁、青春期发育延迟、脏器肿大、黄疸和炎症性肠病家族史。发热、疼痛不在脐周区域、夜间疼痛、红细胞沉降率升高、体重减轻、生长发育障碍和腹部压痛是本研究中提示器质性腹痛诊断的警示信号。

结论

一系列警示信号可增加在RAP患儿中发现器质性腹痛的可能性。

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Iran J Pediatr. 2011 Mar;21(1):33-8.
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Recurrent abdominal pain in children.儿童复发性腹痛。
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Helicobacter pylori infection in Iranian children with recurrent abdominal pain.伊朗反复腹痛儿童的幽门螺杆菌感染
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Aetiology of recurrent abdominal pain in a cohort of Sri Lankan children.一组斯里兰卡儿童复发性腹痛的病因
J Paediatr Child Health. 2008 Apr;44(4):195-200. doi: 10.1111/j.1440-1754.2008.01295.x.
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Familial Mediterranean fever in northwest of Iran (Ardabil): the first global report from Iran.伊朗西北部(阿尔达比勒)的家族性地中海热:来自伊朗的首份全球报告。
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