Micali G, Cook B, Blekys I, Solomon L M
Department of Dermatology, University of Illinois, Chicago, IL 60612.
Pediatr Dermatol. 1990 Mar;7(1):27-32. doi: 10.1111/j.1525-1470.1990.tb01069.x.
The hair of patients with three ectodermal dysplasias--ectrodactyly ectodermal dysplasia clefting syndrome (EEC); orofacial-digital syndrome (OFD) type I; and anhidrotic ectodermal dysplasia syndrome (AED)--were studied by scanning electron microscopy. While no pathognomonic abnormalities were noted for each condition, hair shaft structural defects were evident in all patients studied. The EEC clefting syndrome and OFD I shared the most deforming defects, while AED had fewer.
对患有三种外胚层发育异常疾病的患者的毛发进行了扫描电子显微镜研究，这三种疾病分别是：缺指（趾）-外胚层发育异常-腭裂综合征（EEC）；I型口面指综合征（OFD）；以及无汗性外胚层发育异常综合征（AED）。虽然每种病症均未发现具有诊断意义的异常情况，但在所研究的所有患者中，毛干结构缺陷均很明显。EEC腭裂综合征和I型OFD具有最严重的致畸形缺陷，而AED的缺陷较少。
