Department of Obstetrics and Gynaecology, Fu Zhou General Hospital, 156, xi'er huan North Road, Fu Zhou, 350025, Fujian, China.
Arch Gynecol Obstet. 2013 Aug;288(2):355-9. doi: 10.1007/s00404-013-2713-3. Epub 2013 Feb 23.
This study is to analyze prospectively the anatomical and functional outcomes of transvaginal pelvic reconstructive surgery using the Prolift™ system for pelvic organ prolapse (POP) with hysterectomy.
A prospective, observational, noncomparative study was conducted in 80 patients with prolapse ≥ 2. Postoperative pelvic organ prolapse quantification stage was the main outcome measure. Anatomical cure was defined as vaginal vault stage 0 and improvement as stage 1. Secondary outcomes include pelvic floor distress inventory-20, incontinence impact questionnaire short form-7, and pelvic floor impact questionnaire short form-7.
A total of 80 patients were recruited. The cure and improvement rates were 96.3 % (77/80) and 3.7 % (3/80) respectively at 1 year. At the follow-up of 3-years, the cure rates were 93.3 % (70/75). Among the five patients, three had stage 2 anterior wall prolapse, two had stage 2 posterior wall prolapse. Only one patient with intraoperative adverse event (rectal perforation) was encountered. Postoperative complications included prolonged catheterization in three patients (3.7 %), postoperative stress urinary incontinence in five patients (6.25 %) and asymptomatic mesh extrusions in five patients (6.25 %). All of them occurred within 1 year follow-up. Significant improvements in quality of life were detected at 1 and 3 years compared with baseline.
The total Prolift™ system surgery represents a safe, simple and useful treatment for severe POP with satisfactory objective clinical outcomes.
本研究旨在前瞻性分析经阴道盆腔重建手术（Pro lift 系统）治疗脱垂≥2 度的脱垂患者的解剖和功能结果。
对 80 例脱垂患者进行前瞻性、观察性、非对照研究。主要观察指标为术后盆腔器官脱垂定量分期。解剖治愈定义为阴道穹窿分期 0 级，改善定义为 1 级。次要结果包括盆底窘迫量表 20 分、尿失禁影响问卷短表 7 分和盆底影响问卷短表 7 分。
共招募 80 例患者。1 年时，治愈率和改善率分别为 96.3%（77/80）和 3.7%（3/80）。3 年随访时，治愈率为 93.3%（70/75）。5 例患者中，3 例前壁 2 度脱垂，2 例后壁 2 度脱垂。仅 1 例术中发生不良事件（直肠穿孔）。术后并发症包括 3 例（3.7%）导尿时间延长，5 例（6.25%）术后压力性尿失禁，5 例（6.25%）无症状网片突出，均发生在 1 年随访内。与基线相比，1 年和 3 年时生活质量均显著改善。
Pro lift 系统治疗重度 POP 安全、简单、有效，可获得满意的客观临床疗效。
