Trim Cynthia M, Hofmeister Erik H, Peroni John F, Thoresen Merrilee
Department of Large Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens, GA, USA.
Vet Anaesth Analg. 2013 Nov;40(6):e31-9. doi: 10.1111/vaa.12018. Epub 2013 Feb 25.
To determine the accuracy of an oscillometric blood pressure monitor in anesthetized sheep.
Prospective study.
Twenty healthy adult sheep, 11 males and nine females, weighing 63.6 ± 8.6 kg.
After premedication with buprenorphine or transdermal fentanyl, anesthesia was induced with ketamine-midazolam and maintained with isoflurane and ketamine, 1.2 mg kg(-1) hour(-1), ± lidocaine, 3 mg kg(-1) hour(-1). Invasive blood pressure measurements were obtained from an auricular arterial catheter and noninvasive measurements were from a cuff on the metatarsus or antebrachium. Simultaneous invasive and noninvasive measurements were recorded over a range (55-111 mmHg) of mean arterial pressures (MAP). Isoflurane concentration was increased to decrease MAP and decreasing the isoflurane concentration and infusing dobutamine achieved higher pressures. Invasive and noninvasive measurements were compared.
Correlation (R(2)) was good between the two methods of measurement (average of three consecutive readings) for systolic (SAP) (0.87), diastolic (DAP) (0.86), and mean (0.90) arterial pressures (p < 0.001). Bias ± SD between noninvasive and invasive measurements for SAP was 3 ± 8 mmHg, for DAP was -10 ± 7 mmHg, and MAP was -7 ± 6 mmHg. There was no significant difference between the average of three measurements and use of the first measurement. Correlations using the first measurement were SAP (0.82), DAP (0.84), and MAP (0.89). Bias ± SD for SAP was 3 ±10 mmHg, for DAP was -11 ± 7 mmHg, and MAP was -7 ± 6 mmHg. The oscillometric monitor slightly overestimated SAP and underestimated DAP and MAP for both average values and the first reading.
This oscillometric model provided MAP measurements that were acceptable by ACVIM standards. MAP measurements with this monitor were lower than those found with the invasive technique so a clinical diagnosis of hypotension may be made in sheep that are not hypotensive.
确定示波法血压监测仪在麻醉绵羊中的准确性。
前瞻性研究。
20只健康成年绵羊，11只雄性，9只雌性，体重63.6±8.6千克。
用丁丙诺啡或透皮芬太尼进行预处理后，用氯胺酮-咪达唑仑诱导麻醉，并用异氟烷和氯胺酮（1.2毫克/千克/小时）维持麻醉，±利多卡因（3毫克/千克/小时）。通过耳动脉导管进行有创血压测量，通过跗骨或前臂上的袖带进行无创测量。在平均动脉压（MAP）范围（55-111毫米汞柱）内同时记录有创和无创测量值。增加异氟烷浓度以降低MAP，降低异氟烷浓度并输注多巴酚丁胺以获得更高的血压。比较有创和无创测量值。
两种测量方法（连续三次读数的平均值）之间的收缩压（SAP）（0.87）、舒张压（DAP）（0.86）和平均动脉压（0.90）的相关性良好（p<0.001）。无创和有创测量的SAP偏差±标准差为3±8毫米汞柱，DAP为-10±7毫米汞柱，MAP为-7±6毫米汞柱。三次测量的平均值与第一次测量的使用之间没有显著差异。使用第一次测量的相关性为SAP（0.82）、DAP（0.84）和MAP（0.89）。SAP的偏差±标准差为3±10毫米汞柱，DAP为-11±7毫米汞柱，MAP为-7±6毫米汞柱。对于平均值和第一次读数，示波监测仪均略微高估了SAP，低估了DAP和MAP。
该示波模型提供的MAP测量值符合美国兽医内科学会（ACVIM）标准。使用该监测仪测量的MAP低于有创技术测量的值，因此在并非低血压的绵羊中可能会做出低血压的临床诊断。
