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普通感冒是一种临床实体还是一种文化概念?

Is the common cold a clinical entity or a cultural concept?

机构信息

Cardiff School of Biosciences, Cardiff University, UK.

出版信息

Rhinology. 2013 Mar;51(1):3-8. doi: 10.4193/Rhino12.123.

Abstract

Common cold is the most common infectious disease of mankind and the term is widely used in the clinical literature as though it were a defined clinical syndrome. Clinical studies on this syndrome often use elaborate symptom scoring systems to diagnose a common cold. The symptom scores are based on a study conducted over 50 years ago to retrospectively diagnose experimental cold and this method cannot be applied to diagnosis of common cold in the community. Diagnosis of the common cold by virology is not feasible because of the number of viruses and the variability in the disease states caused by the viruses. Because of the familiarity of subjects with common cold and the variability in symptomatology it seems a more reasonable approach to use self-diagnosis of common cold for clinical research studies and accept that the common cold is a cultural concept and not a clinical entity.

摘要

普通感冒是人类最常见的传染病,在临床文献中广泛使用这个术语,就好像它是一种明确的临床综合征。对这种综合征的临床研究经常使用精心设计的症状评分系统来诊断普通感冒。这些症状评分是基于 50 多年前进行的一项研究,用于回顾性诊断实验性感冒,这种方法不能用于社区普通感冒的诊断。由于病毒的数量和病毒引起的疾病状态的可变性,通过病毒学诊断普通感冒是不可行的。由于研究对象对普通感冒的熟悉程度以及症状表现的可变性,因此使用普通感冒的自我诊断来进行临床研究似乎是一种更合理的方法,并接受普通感冒是一种文化概念,而不是一种临床实体。

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