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用于治疗普通感冒的芳香软膏:科学是怎么说的?

Aromatic ointments for the common cold: what does the science say?

作者信息

Smith Andrew, Matthews Oliver

机构信息

School of Psychology, Cardiff University, Cardiff, UK.

Procter and Gamble UK, Weybridge, Surrey, UK.

出版信息

Drugs Context. 2022 Aug 1;11. doi: 10.7573/dic.2022-5-6. eCollection 2022.

Abstract

BACKGROUND

Upper respiratory tract infections occur with an annual incidence of 17.2 billion cases globally. The negative impact that symptoms have on sleep is thought to slow the recovery process. Plant-derived aromatics have been used since ancient times to treat respiratory illnesses. In this narrative review, we summarize the use of aromatics for the symptomatic relief of upper respiratory tract infections and how this affects sleep quality.

METHODS

Literature searches were conducted using a series of search terms and results were screened for relevance. Additional references were included according to the expert knowledge of the authors.

DISCUSSION

Multiple studies have observed that essential oil mixtures of aromatics enhance symptom relief for upper respiratory tract infections and their inhalation has been reported to have antitussive effects. Clinical trials assessing the efficacy of an ointment containing menthol, eucalyptus and camphor found patients to experience faster nasal cooling and decongestion times. Treatment with the same ointment also resulted in significant improvements in reported sleep quality. Aromatic treatment did not improve objective nasal airway measures in any of the studies.

CONCLUSION

Whilst not affecting objective measures of nasal airway resistance, the use of aromatics leads to improvements in a number of subjective sensations associated with the common cold. Such benefits result in better sleep, which likely aids recovery. Therefore, aromatics remain a well tolerated and effective option for the symptomatic relief of upper respiratory tract infections.

摘要

背景

全球上呼吸道感染的年发病例数达172亿例。症状对睡眠的负面影响被认为会减缓康复进程。植物源芳香剂自古以来就被用于治疗呼吸道疾病。在这篇叙述性综述中,我们总结了芳香剂用于缓解上呼吸道感染症状的情况以及其对睡眠质量的影响。

方法

使用一系列检索词进行文献检索,并筛选结果的相关性。根据作者的专业知识纳入其他参考文献。

讨论

多项研究观察到,芳香剂的精油混合物可增强上呼吸道感染症状的缓解,据报道吸入这些混合物具有镇咳作用。评估含有薄荷醇、桉叶油和樟脑的软膏疗效的临床试验发现,患者的鼻腔冷却和减轻充血时间更快。使用同一种软膏治疗也使报告的睡眠质量有显著改善。在任何研究中,芳香疗法均未改善客观的鼻气道指标。

结论

虽然芳香剂不影响鼻气道阻力的客观指标,但使用芳香剂可改善与普通感冒相关的多种主观感受。这些益处可带来更好的睡眠,这可能有助于康复。因此,芳香剂仍然是一种耐受性良好且有效的缓解上呼吸道感染症状的选择。

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本文引用的文献

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Impact of partial sleep deprivation on immune markers.部分睡眠剥夺对免疫标志物的影响。
Sleep Med. 2013 Oct;14(10):1031-4. doi: 10.1016/j.sleep.2013.07.001. Epub 2013 Aug 28.

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