Hillaire M C, Gomez L, Jouany J P
I.N.R.A., Centre de Recherches de Clermont-Theix, Station de Recherches sur la Nutrition des Herbivores, Ceyrat, France.
Arch Tierernahr. 1990 Jan-Feb;40(1-2):65-74. doi: 10.1080/17450399009428384.
An in vitro study on a "batch" type fermentation system was carried out in order to evaluate the effect of different doses of a new ionophore antibiotic, abierixin, on the rumen fermentation parameters. The reaction of microorganisms to the antibiotic were determined according to the nature of the nitrogen introduced into the fermenter: ammonium sulfate alone or complemented with protein nitrogen (peanut meal or a mixed pelleted feed). This molecule had a protective effect with respect to dietary protein degradation in the rumen, at the lowest dose tested (13.5 ppm). The dose (8 ppm) used with the pelleted feed led to a decrease in the protein degradability but the significant threshold was not reached. Abierixin failed to modify bacterial ammonia uptake with the nitrogen sources used in our experiment. In addition, it had no effect on rumen fermentations. It neither led to any alteration in the total VFA and gas productions during 6 hours of fermentation, nor on their molar composition, whatever the dose of antibiotic used and the nitrogen source considered.
为了评估不同剂量的新型离子载体抗生素阿比瑞新对瘤胃发酵参数的影响，开展了一项关于“批次”型发酵系统的体外研究。根据引入发酵罐的氮的性质来确定微生物对抗生素的反应：单独使用硫酸铵或补充蛋白质氮（花生粕或混合颗粒饲料）。在测试的最低剂量（13.5 ppm）下，该分子对瘤胃中膳食蛋白质的降解具有保护作用。与颗粒饲料一起使用的剂量（8 ppm）导致蛋白质降解率下降，但未达到显著阈值。在我们的实验中，阿比瑞新未能改变所用氮源的细菌氨摄取。此外，它对瘤胃发酵没有影响。无论使用的抗生素剂量和所考虑的氮源如何，在6小时的发酵过程中，它既不会导致总挥发性脂肪酸和气体产量的任何变化，也不会影响它们的摩尔组成。
