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Benign cystic ovarian teratoma with a fistula into the small and large bowel.良性囊性卵巢畸胎瘤伴瘘管入小肠和大肠。
Obstet Gynecol. 2012 Feb;119(2 Pt 2):434-436. doi: 10.1097/AOG.0b013e3182319185.
2
A phase 3 trial of bevacizumab in ovarian cancer.贝伐珠单抗治疗卵巢癌的 III 期临床试验。
N Engl J Med. 2011 Dec 29;365(26):2484-96. doi: 10.1056/NEJMoa1103799.
3
Incorporation of bevacizumab in the primary treatment of ovarian cancer.贝伐珠单抗在卵巢癌初始治疗中的应用。
N Engl J Med. 2011 Dec 29;365(26):2473-83. doi: 10.1056/NEJMoa1104390.
4
A giant gas-filled abdominal mass in an elderly female: a case report.老年女性巨大充气性腹部肿块:病例报告。
World J Gastroenterol. 2011 Aug 21;17(31):3659-62. doi: 10.3748/wjg.v17.i31.3659.
5
Bevacizumab plus microtubule targeting agents in heavily pre-treated ovarian cancer patients: a retrospective study.贝伐单抗联合微管靶向药物治疗高度预处理的卵巢癌患者:一项回顾性研究。
Bull Cancer. 2011 Oct;98(9):80-9. doi: 10.1684/bdc.2011.1436.
6
Successful closure of anal cancer-related fistulas with upfront intra-arterial chemotherapy: a report of 8 cases.经动脉内化疗一期治疗肛门癌相关瘘管的成功闭合:8 例报告。
Dis Colon Rectum. 2011 May;54(5):566-9. doi: 10.1007/DCR.0b013e31820d8333.
7
Perforation of a malignant ovarian tumor into the recto-sigmoid colon.卵巢恶性肿瘤穿孔至直肠-乙状结肠。
Acta Obstet Gynecol Scand. 2010 Oct;89(10):1362-3. doi: 10.3109/00016349.2010.501857.
8
The risk of gastrointestinal perforation and/or fistula in patients with recurrent ovarian cancer receiving bevacizumab compared to standard chemotherapy: a retrospective cohort study.复发性卵巢癌患者接受贝伐单抗治疗与标准化疗相比发生胃肠道穿孔和/或瘘管的风险:一项回顾性队列研究。
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9
Disseminated retroperitoneal choriocarcinoma with open fistula to intestine. "Restitutio ad integrum" with chemotherapy alone.
Clin Transl Oncol. 2006 Jun;8(6):453-5. doi: 10.1007/s12094-006-0201-y.
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Chemotherapy in the management of advanced gastointestinal non-Hodgkin's lymphoma complicated with entero-cutaneous fistula: a case report.
Afr J Med Med Sci. 2005 Jun;34(2):199-200.

初始表现为晚期卵巢癌的肠-附件瘘管的保守治疗。

Conservative management for an entero-adnexal fistula at initial presentation of advanced ovarian carcinoma.

机构信息

Department of Oncology, Clalit Health Services, Lin Medical Center, Haifa, Israel.

出版信息

Curr Oncol. 2013 Feb;20(1):e44-7. doi: 10.3747/co.20.1196.

DOI:10.3747/co.20.1196
PMID:23443318
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3557342/
Abstract

Gastrointestinal fistulae can occur in ovarian cancer patients, usually in the setting of advanced relapsed disease. Treatment typically involves immediate surgery.Here, we describe a case of an abscess resulting from an intestinal fistula as the first manifestation of advanced epithelial ovarian cancer, and we review the current literature on this subject. The patient was successfully treated with a combination of chemotherapy, antibiotics, and delayed surgery. Optimal debulking was achieved without a need for bowel resection.This report is the first of conservative management of a fistula in an ovarian cancer patient in the chemotherapy-naïve setting.

摘要

胃肠道瘘可发生在卵巢癌患者中,通常发生在晚期复发性疾病的情况下。治疗通常需要立即手术。在这里,我们描述了一例因肠瘘导致脓肿的病例,这是晚期上皮性卵巢癌的首发表现,并回顾了该主题的现有文献。患者成功地接受了化疗、抗生素和延迟手术的联合治疗。在无需肠切除的情况下实现了最佳的肿瘤减灭术。本报告是首例在化疗初治的卵巢癌患者中采用保守治疗瘘管的报告。