Division of Nephrology and Hypertension, Department of Medicine, University of Miami Miller School of Medicine, 1120 NW 14th Street, Suite 815, Miami, Florida 33136, USA.
Kidney Int. 2013 Mar;83(3):356-8. doi: 10.1038/ki.2012.438.
Previously, recipients of a simultaneous pancreas-kidney transplant versus a kidney transplant alone were thought to have higher fracture risk. Using a large US registry, Nikkel et al. observed lower rates of fracture hospitalization among patients with type 1 diabetes after simultaneous pancreas-kidney compared with kidney transplantation alone, particularly among men. It is not known whether the apparent benefit of simultaneous pancreas-kidney transplantation is due to improved bone strength or fewer falls, but these findings may influence transplant decision making.
此前，人们认为接受胰肾联合移植与单独接受肾移植的患者骨折风险更高。Nikkel 等人利用美国大型注册研究发现，与单独肾移植相比，1 型糖尿病患者在接受胰肾联合移植后骨折住院率较低，尤其是男性。尚不清楚胰肾联合移植的明显益处是由于骨强度改善还是跌倒减少，但这些发现可能会影响移植决策。
