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[在动物实验中使用Vilan 500对静脉床进行治疗性栓塞]

[Therapeutic embolization of the venous bed using Vilan 500 in animal experiments].

作者信息

Janík V, Kolihová E, Peregrin J H, Schlegerová D, Vrána M, Belán A

机构信息

Ustrední radiodiagnostické oddĕlení FN, Praha, Motol.

出版信息

Cesk Radiol. 1990 Jan;44(1):44-50.

PMID:2344656
Abstract

The experiment in four dogs verified a suitability of the Czechoslovak preparation Vilan 500, a copolymer of polyvinyl acetate - polyvinyl alcohol in 93% ethanol, for the embolism of venous vascular bed in the percutaneous, transfemoral catheterization way. In all four cases there was a complete occlusion of embolized spermatic or pararenal veins, verified by a control angiography after one hour and after three months. The prepared venous samples were also examined by histology and changes indicating intraluminar thrombotization and subsequent fibrous reconstruction were observed. In view of the results reached it may be concluded that the catheterization technique and the use of Vilan 500 is suitable as an alternative of non-surgical solution of varicocele.

摘要

在四只狗身上进行的实验证实了捷克斯洛伐克制剂Vilan 500(一种聚醋酸乙烯酯-聚乙烯醇共聚物在93%乙醇中的溶液)适用于经皮股动脉导管插入术对静脉血管床进行栓塞。在所有四个案例中,栓塞的精索静脉或肾旁静脉均完全闭塞,这在一小时后和三个月后通过对照血管造影得到证实。制备的静脉样本也进行了组织学检查,观察到了表明管腔内血栓形成及随后纤维重建的变化。鉴于所取得的结果,可以得出结论,导管插入技术和Vilan 500的使用适合作为精索静脉曲张非手术治疗方案的替代方法。

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