Center for Primary Health Care Research, Lund University/Region Skåne, CRC, Skåne University Hospital, Building 28, Floor 11, Jan Waldenströms gata 35, SE-205 02 Malmö, Sweden.
Europace. 2013 Aug;15(8):1119-27. doi: 10.1093/europace/eut019. Epub 2013 Feb 27.
Several cardiovascular disorders (CVDs) are strongly associated with socioeconomic disparities and neighbourhood deprivation. However, no study has determined whether neighbourhood deprivation is associated with atrial fibrillation (AF). We aimed to determine whether there is an association between neighbourhood deprivation and hospitalization for AF.
The entire Swedish population aged 25-74 years was followed from 1 January 2000 until hospitalization for AF, death, emigration, or the end of the study period (31 December 2008). Data were analysed by multilevel logistic regression, with individual-level characteristics (age, marital status, family income, educational attainment, migration status, urban/rural status, mobility, and comorbidity) at the first level and level of neighbourhood deprivation at the second level. Neighbourhood deprivation was significantly associated with AF hospitalization rate in women [odds ratio (OR) = 1.40, 95% confidence interval (CI) 1.35-1.47], but not men (OR = 1.01, 95% CI 0.97-1.04). The odds of AF in women living in the most deprived neighbourhoods remained significant after adjustment for age and individual-level socioeconomic characteristics (OR = 1.12, 95% 1.08-1.16). However, in the full model, which took account of age, individual-level socioeconomic characteristics, and comorbidities (chronic lower respiratory diseases, OR = 1.30; type 2 diabetes, OR = 1.32; alcoholism and alcohol-related liver disease, OR = 1.57; hypertension, OR = 2.84; obesity, OR = 1.80; heart failure, OR = 7.40; coronary heart disease, OR = 1.81; and hyperthyroidism, OR = 6.79), the odds of AF did not remain significant in women in the most deprived neighbourhoods (OR = 1.03, 95% CI 0.99-1.07).
Neighbourhood deprivation and socioeconomic disparities are not independently associated with hospitalized AF in contrast to many other CVDs.
多种心血管疾病（CVD）与社会经济差异和邻里贫困密切相关。然而，尚无研究确定邻里贫困是否与心房颤动（AF）有关。我们旨在确定邻里贫困与 AF 住院治疗之间是否存在关联。
从 2000 年 1 月 1 日起，对所有 25-74 岁的瑞典人进行了随访，直到 AF 住院治疗、死亡、移民或研究结束（2008 年 12 月 31 日）。使用个体水平特征（年龄、婚姻状况、家庭收入、教育程度、移民状况、城乡状况、流动性和合并症）一级和邻里贫困水平二级的多水平逻辑回归进行数据分析。邻里贫困与女性的 AF 住院率显著相关[比值比（OR）=1.40，95%置信区间（CI）1.35-1.47]，但与男性无关（OR=1.01，95%CI 0.97-1.04）。在调整年龄和个体社会经济特征后，居住在最贫困社区的女性患 AF 的几率仍然显著（OR=1.12，95%CI 1.08-1.16）。然而，在考虑年龄、个体社会经济特征和合并症（慢性下呼吸道疾病，OR=1.30；2 型糖尿病，OR=1.32；酒精中毒和酒精相关肝病，OR=1.57；高血压，OR=2.84；肥胖，OR=1.80；心力衰竭，OR=7.40；冠心病，OR=1.81；和甲状腺功能亢进症，OR=6.79）的全模型中，最贫困社区女性的 AF 发病几率不再显著（OR=1.03，95%CI 0.99-1.07）。
与许多其他 CVD 不同，邻里贫困和社会经济差异与住院治疗的 AF 无关。
