• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

抓住机遇:对癫痫更宽泛的定义可能带来更好的治疗方法。

Seizing an opportunity: broader definitions of epilepsy may lead to better treatments.

作者信息

Scharfman Helen E

出版信息

Cerebrum. 2010 Sep;2010:18. Epub 2010 Sep 22.

PMID:23447764
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2997748/
Abstract

There is not just one type of epilepsy. While some forms of the disease are characterized by convulsive seizures, others involve seizures that are barely noticeable. Seizures can occur for many reasons: they can be caused by genetic mutations, injury, or infection early in life. In addition, events in daily life, such as stress, or normal variations in hormones, such as estrogen and testosterone, can influence brain activity and therefore influence seizures. By considering the powerful interactions between the brain and the endocrine system, this influence of hormones on seizures can be understood and new treatment options can be considered.

摘要

癫痫不止一种类型。虽然有些形式的癫痫以抽搐性发作特征,但其他类型的癫痫发作几乎难以察觉。癫痫发作的原因有很多:可能由基因突变、损伤或早年感染引起。此外,日常生活中的事件,如压力,或激素的正常变化,如雌激素和睾酮,都可能影响大脑活动,进而影响癫痫发作。通过考虑大脑与内分泌系统之间的强大相互作用,可以理解激素对癫痫发作的这种影响,并考虑新的治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5a9/3574764/d0ee40f8f759/cerebrum-18-10-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5a9/3574764/6094c990885c/cerebrum-18-10-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5a9/3574764/d0ee40f8f759/cerebrum-18-10-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5a9/3574764/6094c990885c/cerebrum-18-10-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5a9/3574764/d0ee40f8f759/cerebrum-18-10-g002.jpg

相似文献

1
Seizing an opportunity: broader definitions of epilepsy may lead to better treatments.抓住机遇:对癫痫更宽泛的定义可能带来更好的治疗方法。
Cerebrum. 2010 Sep;2010:18. Epub 2010 Sep 22.
2
Interactions between hormones and epilepsy.激素与癫痫之间的相互作用。
Seizure. 2015 May;28:3-11. doi: 10.1016/j.seizure.2015.02.012. Epub 2015 Feb 23.
3
Pre-hospital and emergency department treatment of convulsive status epilepticus in adults: an evidence synthesis.成人惊厥性癫痫持续状态的院前和急诊处理:证据综合。
Health Technol Assess. 2022 Mar;26(20):1-76. doi: 10.3310/RSVK2062.
4
The control of convulsive seizures by endocrine therapy; a preliminary report.内分泌疗法对惊厥性癫痫的控制;初步报告。
Conn State Med J. 1952 Sep;16(9):679-81.
5
Hormones and epilepsy through the lifetime.一生中的激素与癫痫
Epilepsia. 1992;33 Suppl 4:S49-61. doi: 10.1111/j.1528-1157.1992.tb06227.x.
6
The influence of gonadal hormones on neuronal excitability, seizures, and epilepsy in the female.性腺激素对雌性动物神经元兴奋性、癫痫发作及癫痫的影响。
Epilepsia. 2006 Sep;47(9):1423-40. doi: 10.1111/j.1528-1167.2006.00672.x.
7
Novel features for capturing temporal variations of rhythmic limb movement to distinguish convulsive epileptic and psychogenic nonepileptic seizures.捕捉节律性肢体运动时间变化的新特征,以区分癫痫性抽搐和非癫痫性精神运动发作。
Epilepsia. 2019 Jan;60(1):165-174. doi: 10.1111/epi.14619. Epub 2018 Dec 9.
8
Hormonal considerations in women with seizures.癫痫女性患者的激素相关考量
Arch Neurol. 1988 Nov;45(11):1267-70. doi: 10.1001/archneur.1988.00520350105025.
9
Idiopathic (Genetic) Generalized Epilepsy特发性(遗传性)全身性癫痫
10
Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data.抗癫痫药物单药治疗癫痫:一项个体参与者数据的网络荟萃分析。
Cochrane Database Syst Rev. 2022 Apr 1;4(4):CD011412. doi: 10.1002/14651858.CD011412.pub4.

本文引用的文献

1
Seizure exacerbation and hormonal cycles in women with epilepsy.癫痫女性的发作恶化与激素周期。
Epilepsy Res. 2010 Aug;90(3):214-20. doi: 10.1016/j.eplepsyres.2010.05.003. Epub 2010 Jun 9.
2
Bifrontal, bitemporal and right unilateral electrode placement in ECT: randomised trial.额颞双侧和右侧单侧电极放置在电抽搐治疗中的随机试验。
Br J Psychiatry. 2010 Mar;196(3):226-34. doi: 10.1192/bjp.bp.109.066183.
3
Experts describe "spectrum" of epilepsy.专家描述癫痫的“谱系”。
JAMA. 2010 Jan 27;303(4):313-4. doi: 10.1001/jama.2009.1977.
4
New tricks by an old dogma: mechanisms of the Organizational/Activational Hypothesis of steroid-mediated sexual differentiation of brain and behavior.旧有教条的新花样:类固醇介导的脑与行为性别分化的组织/激活假说机制
Horm Behav. 2009 May;55(5):655-65. doi: 10.1016/j.yhbeh.2009.02.012.
5
Laterality and location influence catamenial seizure expression in women with partial epilepsy.偏侧性和部位影响部分性癫痫女性患者的经期癫痫发作表现。
Neurology. 2009 Jul 21;73(3):223-7. doi: 10.1212/WNL.0b013e3181ae7adf.
6
The organizational-activational hypothesis as the foundation for a unified theory of sexual differentiation of all mammalian tissues.组织-激活假说作为所有哺乳动物组织性别分化统一理论的基础。
Horm Behav. 2009 May;55(5):570-8. doi: 10.1016/j.yhbeh.2009.03.011.
7
Seizures and reproductive function: insights from female rats with epilepsy.癫痫发作与生殖功能:来自癫痫雌性大鼠的见解
Ann Neurol. 2008 Dec;64(6):687-97. doi: 10.1002/ana.21518.
8
Mechanisms mediating oestradiol modulation of the developing brain.介导雌二醇对发育中大脑调节作用的机制。
J Neuroendocrinol. 2008 Jun;20(6):777-83. doi: 10.1111/j.1365-2826.2008.01723.x.
9
Hormone replacement therapy: will it affect seizure control and AED levels?激素替代疗法:它会影响癫痫控制和抗癫痫药物水平吗?
Seizure. 2008 Mar;17(2):176-80. doi: 10.1016/j.seizure.2007.11.026. Epub 2008 Jan 9.
10
Catamenial epilepsy: definition, prevalence pathophysiology and treatment.经期癫痫:定义、患病率、病理生理学及治疗
Seizure. 2008 Mar;17(2):151-9. doi: 10.1016/j.seizure.2007.11.014.