Adams P C
Department of Medicine, University Hospital, University of Western Ontario, London, Canada.
Dig Dis Sci. 1990 Jun;35(6):690-2. doi: 10.1007/BF01540168.
Ninety-two families with familial hemochromatosis were reviewed and analyzed in regard to hepatic iron and the value of the hepatic iron index (hepatic iron/age). Hepatic iron was measured in 29 hemochromatosis homozygotes, in 10 hemochromatosis heterozygotes, and in 30 control patients with other liver diseases. Hepatic iron content increased with age in homozygotes. Hepatic iron index differentiated homozygotes from heterozygotes (P less than 0.05) and heterozygotes from controls (P less than 0.05). The hepatic iron index is a useful measurement in the diagnosis and management of patients with familial hemochromatosis.
对92个患有家族性血色素沉着症的家庭进行了回顾分析，涉及肝脏铁含量以及肝脏铁指数（肝脏铁含量/年龄）的值。对29名血色素沉着症纯合子、10名血色素沉着症杂合子以及30名患有其他肝脏疾病的对照患者进行了肝脏铁含量测量。纯合子的肝脏铁含量随年龄增长而增加。肝脏铁指数可区分纯合子与杂合子（P<0.05）以及杂合子与对照患者（P<0.05）。肝脏铁指数在家族性血色素沉着症患者的诊断和管理中是一项有用的测量指标。
