Celik Tuba, Yuksel Dilek, Kosker Mustafa, Turkoglu Elif Betul
Bolu Gerede State Hospital, Department of Ophthalmology, Bolu, Turkey.
Semin Ophthalmol. 2013 Mar;28(2):91-3. doi: 10.3109/08820538.2012.760624.
To describe an unusual case of oculoglandular tularemia associated with unilateral acute dacryocystitis and purulent conjunctivitis with 18 weeks pregnancy.
It is difficult to culture francisella tularensis on media so serological tests such as micro-agglutination methods are used to diagnose the infection. PCR test results were weak positive. The serum sample was analyzed for the presence of f. tularensis antibody, which was determined positive with a titer of 1/160.
Oral amoksicilin-clavulonic acid treatment was applied to the patient because of the side-effects of other antibiotics on the fetus. Dacryocystitis was surgically drained but relapsed a few weeks later, so it was drained again and a ciprofloksasin-impregnated sponge was placed into the tissue defect that occured after drainage. No relapses were seen after recovery of dacryocystitis.
Oculoglandular tularemia is not only suspected in cases who complain of fever, cervical lymphadenopathy and purulent conjunctivitis, it should also be suspected in cases who are admitted to the hospital with acute dacryocystitis, which is a rare component of oculoglandular syndrome.
描述一例与单侧急性泪囊炎和脓性结膜炎相关的眼腺型兔热病罕见病例,患者处于妊娠18周。
土拉弗朗西斯菌在培养基上难以培养,因此采用血清学检测方法如微量凝集法来诊断感染。聚合酶链反应(PCR)检测结果为弱阳性。对血清样本进行土拉弗朗西斯菌抗体检测,结果呈阳性,滴度为1/160。
由于其他抗生素对胎儿有副作用,故对患者应用口服阿莫西林 - 克拉维酸治疗。泪囊炎进行了手术引流,但几周后复发,于是再次引流,并将含环丙沙星的海绵置于引流后出现的组织缺损处。泪囊炎治愈后未见复发。
眼腺型兔热病不仅应怀疑于主诉发热、颈部淋巴结病和脓性结膜炎的患者,对于因急性泪囊炎入院的患者也应怀疑,急性泪囊炎是眼腺综合征的罕见组成部分。