Division of Behavioral Medicine and Clinical Psychology, Center for Promotion of Adherence and Self-Management, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229, USA.
J Pediatr Psychol. 2013 Jul;38(6):649-63. doi: 10.1093/jpepsy/jss175. Epub 2013 Feb 28.
To evaluate the effectiveness of an adherence promotion intervention provided to patients and families referred to a clinical service.
6 patients and their caregivers representing 5 different chronic conditions were seen for comprehensive psychological intervention that was evaluated based on electronic monitoring of adherence to prescribed oral medication.
Time series analysis (Auto-Regressive Integrated Moving Average) indicated that for each of the 6 cases, treatment adherence increased during the intervention phase relative to nonintervention periods, but for 5 of these 6 patients, adherence decreased during the follow-up period (p < .05).
Comprehensive adherence promotion strategies delivered in standard clinical practice were effective, but the effects did not persist after treatment. Future adherence promotion interventions should focus on sustaining intervention effects.
评估为临床服务转介的患者和家属提供的依从性促进干预措施的效果。
对 6 名患者及其 5 名不同慢性疾病的照顾者进行全面的心理干预，根据电子监测口服药物的遵医嘱情况对干预进行评估。
时间序列分析（自回归积分移动平均）表明，对于这 6 例中的每一例，与非干预期相比，干预期的治疗依从性有所提高，但其中 5 例在随访期依从性下降（p <.05）。
在标准临床实践中提供的综合依从性促进策略是有效的，但治疗后效果并未持续。未来的依从性促进干预措施应侧重于维持干预效果。
