Jayaramakrishnan Kumara, Wotton Robin, Bradley Amy, Naidu Babu
Department of Thoracic Surgery, Heart of England NHS Foundation Trust, Birmingham, UK.
Interact Cardiovasc Thorac Surg. 2013 Jun;16(6):865-70. doi: 10.1093/icvts/ivt045. Epub 2013 Feb 28.
A best evidence topic was written according to a structured protocol. The question addressed was 'Does repair of pectus excavatum (PE) improve cardiopulmonary function?' One hundred and sixty-eight papers were found using the reported search, 19 level III evidence papers and three meta-analyses were relevant. Studies were divided into four groups based on the surgical technique applied and pulmonary and cardiac functions in these groups were analysed. The meta-analyses show conflicting results for improvements in pulmonary and cardiac functions when comparing surgical techniques, while four more recent studies show improved long-term results using the Nuss technique. The best evidence of papers studying the PE repair using the minimally invasive Nuss technique demonstrates a decrease in pulmonary function during the early postoperative period, however, there is a small but significant improvement during the late postoperative period and after bar removal. The best evidence for cardiac function in this group suggests an early improvement that is sustained during further follow-up. The best evidence of papers studying the PE repair using the Ravitch technique shows that pulmonary function decreased during the early postoperative period, however, there is a small but significant improvement during the late postoperative period. The best evidence for cardiac function in this group suggests an early improvement that is sustained during further follow-up. The best evidence of papers studying the PE repair using other techniques (modified Daniel's technique, modified Baronofsky's technique, sterno-costal turn-over technique and sterno-costal elevation technique) or where surgical techniques used were not described (preceding year 1985) suggests that there is no improvement in pulmonary function after surgery. There is some evidence that certain aspects of cardiac function improved after surgery in this group.
根据结构化方案撰写了一个最佳证据主题。所探讨的问题是“漏斗胸(PE)修复术是否能改善心肺功能?”通过报告的检索找到了168篇论文,其中19篇III级证据论文和3篇荟萃分析相关。根据所应用的手术技术将研究分为四组,并分析了这些组中的肺和心脏功能。荟萃分析显示,在比较手术技术时,肺和心脏功能改善的结果相互矛盾,而四项较新的研究表明使用Nuss技术可获得更好的长期结果。使用微创Nuss技术研究PE修复的论文的最佳证据表明,术后早期肺功能下降,然而,术后晚期和取出钢板后有小幅但显著的改善。该组中心脏功能的最佳证据表明早期有改善,并在进一步随访中持续。使用Ravitch技术研究PE修复的论文的最佳证据表明,术后早期肺功能下降,然而,术后晚期有小幅但显著的改善。该组中心脏功能的最佳证据表明早期有改善,并在进一步随访中持续。使用其他技术(改良Daniel技术、改良Baronofsky技术、胸骨-肋骨翻转技术和胸骨-肋骨抬高技术)研究PE修复的论文,或未描述所使用手术技术的论文(1985年之前)的最佳证据表明,术后肺功能没有改善。有一些证据表明该组术后心脏功能的某些方面有所改善。