Selvi E Chandra, K V Rao Kuppu
Assistant Professor, Department of Physiology, Sree Balaji Medical College , Chrompet, Chennai, India .
J Clin Diagn Res. 2013 Jan;7(1):43-5. doi: 10.7860/JCDR/2012/4876.2666. Epub 2013 Jan 1.
The functional residual capacity was given the least importance than the other lung volume parameters. Studies have revealed the restrictive pattern of lung disease in patients with liver cirrhosis. We aimed to analyze the importance of the functional residual capacity and other lung volumes of cirrhotic patients.
Forty (40) patients with cirrhosis (Child's-B) were enrolled in this study. The vital capacity was measured by an instrument called V02 Max 22. The other lung volumes which were measured were derived parameters. The functional residual capacity was measured by the nitrogen wash-out method.
The measured value of the functional residual capacity was below normal as compared to the reference value. The total lung capacity and the vital capacity were positively correlated with the functional residual capacity. The residual volume was found to be increased in twelve out of forty cirrhotic patients.
The functional residual capacity can be determined by the compliance of the lung and the chest wall. The patients with a reduced functional residual capacity may be suffering from dyspnoea, probably due to the restrictive pattern of the lung disease. Hence, the reduced lung volumes of the subjects may be due to the abnormalities in the mechanics of ventilation.
功能残气量相比其他肺容积参数受到的重视最少。研究显示肝硬化患者存在肺部疾病的限制性模式。我们旨在分析肝硬化患者功能残气量及其他肺容积的重要性。
本研究纳入了40例肝硬化（Child's - B级）患者。肺活量通过名为V02 Max 22的仪器测量。所测量的其他肺容积为派生参数。功能残气量通过氮洗脱法测量。
与参考值相比，功能残气量的测量值低于正常水平。肺总量和肺活量与功能残气量呈正相关。40例肝硬化患者中有12例残气量增加。
功能残气量可由肺和胸壁的顺应性决定。功能残气量降低的患者可能患有呼吸困难，这可能是由于肺部疾病的限制性模式所致。因此，受试者肺容积减少可能是由于通气力学异常。
