肝硬化患者的肺功能变化

Pulmonary function changes in cirrhosis of the liver.

作者信息

Yao E H, Kong B C, Hsue G L, Zhou A C, Wang H

出版信息

Am J Gastroenterol. 1987 Apr;82(4):352-4.

Abstract

Pulmonary function tests were performed in 21 cirrhotic patients with ascites, and these were compared with 50 normal controls. The vital capacity in the cirrhotic group was 93.67 +/- 12.5% and in controls was 102.47 +/- 15.22%, p less than 0.05. The maximum voluntary ventilation in cirrhotic patients was 89.33 +/- 25.4% and in controls was 127.48 +/- 28.44%, p less than 0.001. The functional residual capacity in cirrhotic patients was 2362.19 +/- 845.08 ml and in controls was 3085.1 +/- 837.92 ml, p less than 0.01. The total lung capacity in cirrhotic patients was 4675 +/- 1204.09 and in controls was 5791.56 +/- 1033.99, p less than 0.01. The first forced expiratory volume in cirrhotic patients was 70.1 +/- 12.79%, whereas that in controls was 77.74 +/- 9.18%, p less than 0.05. These results imply that in cirrhosis of the liver there are prominent restrictive ventilatory disorders as well as obstructive disorders.

摘要

对21例肝硬化腹水患者进行了肺功能测试，并与50名正常对照者进行了比较。肝硬化组的肺活量为93.67±12.5%，对照组为102.47±15.22%，p<0.05。肝硬化患者的最大自主通气量为89.33±25.4%，对照组为127.48±28.44%，p<0.001。肝硬化患者的功能残气量为2362.19±845.08ml，对照组为3085.1±837.92ml，p<0.01。肝硬化患者的肺总量为4675±1204.09，对照组为5791.56±1033.99，p<0.01。肝硬化患者的第一秒用力呼气量为70.1±12.79%，而对照组为77.74±9.18%，p<0.05。这些结果表明，肝硬化患者存在明显的限制性通气障碍以及阻塞性障碍。