短暂性白血病：白血病还是类白血病？诊断难题。
Transient leukaemia: leukaemia or leukaemoid? A diagnostic dilemma.
作者信息
Marwah Nisha, Modi Shilpi, Gupta Veena, Gupta Sumiti, Singh Gajender, Sen Rajeev
机构信息
Department of Pathology, Pt. B.D. Sharma PGIMS, 2452, Sector-1, HUDA, Rohtak, 124001 India.
出版信息
Indian J Hematol Blood Transfus. 2012 Mar;28(1):47-9. doi: 10.1007/s12288-011-0090-2. Epub 2011 Jul 12.
We report a case of a newborn male who had mongoloid slant and was hypotonic at birth. Routine investigations revealed leucocytosis (WBC > 70,000/cmm) with 50% blasts in peripheral blood film. Marrow examination confirmed the excess of blasts. Karyotyping revealed 47, XY + 21 chromosomes. Due to absence of clinical symptoms, the baby was kept on follow-up without treatment. Within 7 weeks, PBF and bone marrow findings returned to normal, and the child was diagnosed as having Transient leukaemia with Down syndrome.
我们报告一例新生男婴，出生时具有蒙古样斜眼且肌张力减退。常规检查发现白细胞增多（白细胞计数>70,000/立方毫米），外周血涂片中有50%的原始细胞。骨髓检查证实原始细胞过多。核型分析显示有47条染色体，核型为XY，+21。由于没有临床症状，该婴儿未接受治疗，而是进行随访。在7周内，外周血涂片和骨髓检查结果恢复正常，该患儿被诊断为唐氏综合征相关的暂时性白血病。
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