Pluridisciplinary HHT team, Ambroise Paré Hospital, 9, Avenue Charles de Gaulle, 92100 Boulogne-Billancourt, France.
Med Hypotheses. 2013 May;80(5):587-8. doi: 10.1016/j.mehy.2013.01.031. Epub 2013 Feb 27.
Thalidomide has shown its efficacy in the treatment of epistaxis in hereditary hemorrhagic telangiectasia (HHT) patients. We hypothetize that, owing to its anti-inflammatory/antiangiogenic/vascular growth maturation properties, thalidomide should be useful in the prophylaxis and therapy of HHT patients presenting with initial lung involvement.
沙利度胺已显示出在遗传性出血性毛细血管扩张症(HHT)患者鼻出血治疗中的疗效。我们假设,由于其抗炎/抗血管生成/血管生长成熟特性,沙利度胺应该对有初始肺部受累的 HHT 患者的预防和治疗有用。