单侧髁突活动过度患者单光子发射计算机断层扫描骨扫描的观察者间变异。
Interobserver variation of single-photon emission computed tomography bone scans in patients evaluated for unilateral condylar hyperactivity.
机构信息
Department of Oral and Maxillofacial Surgery and Oral Pathology, VU University Medical Center, Amsterdam, The Netherlands.
出版信息
Oral Surg Oral Med Oral Pathol Oral Radiol. 2013 Mar;115(3):399-405. doi: 10.1016/j.oooo.2012.11.016.
OBJECTIVE
This study assessed the quantitative evaluation of the region of interest (ROI) by mean and maximum pixel counts of single-photon emission computed tomography (SPECT) scans in patients with clinical suspicion of unilateral condylar hyperactivity (UCH); the interobserver reliability and the correlation of condylar activity with patient age was determined.
METHODS
Two independent observers analyzed 67 bone SPECT scans. Maximum and mean activity values within an ROI on the mandibular condyle were analyzed; a cutoff value of 55% was used to determine the qualitative outcome.
RESULTS
Excellent interobserver agreement was seen for both maximum (kappa 1.0) and mean activity analysis (kappa 0.94). Maximum and mean condylar activities were strongly correlated (r > 0.98). Maximum and mean condylar activity of the normal condyle decreased significantly with increasing age.
CONCLUSIONS
Maximum and mean condylar activity levels were highly correlated in patients with mandibular asymmetry. An excellent interobserver agreement was found with either maximum or mean condylar activity.
目的
本研究通过对单侧髁突活动过度（UCH）患者单光子发射计算机断层扫描（SPECT）扫描的感兴趣区域（ROI）的平均和最大像素计数进行定量评估，确定 SPECT 扫描在评估单侧髁突活动过度中的应用价值，评估观察者间的可靠性以及髁突活动与患者年龄的相关性。
方法
两名独立观察者分析了 67 例颌骨 SPECT 扫描。对下颌髁 ROI 内的最大和平均活性值进行了分析；使用 55%的截断值来确定定性结果。
结果
最大（kappa 1.0）和平均活性分析（kappa 0.94）的观察者间一致性均极好。最大和平均髁突活性具有很强的相关性（r>0.98）。随着年龄的增长，正常髁突的最大和平均髁突活性显著降低。
结论
在存在下颌骨不对称的患者中，最大和平均髁突活动水平高度相关。最大或平均髁突活性均可获得极好的观察者间一致性。
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