Department of Cardiology, Odense University Hospital, Odense, Denmark.
Am Heart J. 2013 Mar;165(3):393-9. doi: 10.1016/j.ahj.2012.11.009. Epub 2013 Jan 24.
Ongoing development in percutaneous coronary intervention (PCI) techniques and closing devices facilitates same-day-discharge in patients undergoing uncomplicated PCI procedures. We examined the safety and outcome in low-risk patients discharged the same day as PCI with femoral access was performed.
From January 1, 2010, through December 31, 2010, the outcomes of same-day discharge in 355 (19.6%) of in total 1,809 patients undergoing PCI were analyzed. Composite end point included major adverse cardiac or cerebral events and/or bleeding/vascular complications within 24 hours and 30 days. Major adverse cardiac and cerebral events were defined as cardiac death, myocardial infarction, stroke, coronary artery bypass grafting, or repeat PCI.
The mean age of the study population was 64.5 years (40.0-93.0 years), 17.3% of the patients were ≥75 years old. The indication for PCI was: stable angina pectoris (n = 277, 78.0%) and unstable angina pectoris/non-ST-segment elevation myocardial infarction (n = 78, 22.0%). In all patients femoral access was used, and the puncture site was closed with the closing-device AngioSeal. No major adverse cardiac and cerebral events were seen within 24 hours or 30 days except in 1 patient who had target lesion revascularization done as PCI 4 days post-procedure. Three patients had bleeding/vascular complications; 2 patients were re-admitted within 24 hours due to access-site hematomas, which were treated with manual compression and bed-rest regimes. One patient developed a pseudoaneurysm within 12 hours post-procedure.
Same-day-discharge after uncomplicated PCI using femoral access is safe when patients are properly selected. The strategy may improve and benefit health costs in the future.
经皮冠状动脉介入治疗(PCI)技术和封堵装置的不断发展,使得非复杂 PCI 手术的患者能够实现当日出院。我们研究了股动脉入路 PCI 术后当日出院的低危患者的安全性和结局。
2010 年 1 月 1 日至 2010 年 12 月 31 日,分析了 1809 例接受 PCI 治疗的患者中 355 例(19.6%)当日出院的结局。复合终点包括 24 小时和 30 天内的主要心脏或脑不良事件和/或出血/血管并发症。主要心脏和脑不良事件定义为心脏死亡、心肌梗死、卒、冠状动脉旁路移植术或再次 PCI。
研究人群的平均年龄为 64.5 岁(40.0-93.0 岁),17.3%的患者年龄≥75 岁。PCI 的适应证为稳定型心绞痛(n=277,78.0%)和不稳定型心绞痛/非 ST 段抬高型心肌梗死(n=78,22.0%)。所有患者均采用股动脉入路,穿刺部位采用 AngioSeal 封堵装置闭合。除 1 例患者在术后 4 天行 PCI 靶病变血运重建外,24 小时和 30 天内均未见主要心脏和脑不良事件。3 例发生出血/血管并发症;2 例患者因股动脉入路血肿于 24 小时内再次入院,采用手动压迫和卧床休息治疗。1 例患者在术后 12 小时内发生假性动脉瘤。
在适当选择患者的情况下,股动脉入路非复杂 PCI 术后当日出院是安全的。该策略未来可能会改善和有利于医疗成本。