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精神障碍患者物质使用障碍治疗结局的预测因素。

Predictors of substance use disorder treatment outcomes among patients with psychotic disorders.

机构信息

Center for Health Care Evaluation, VA Palo Alto Health Care System, Menlo Park, CA 94025, United States.

出版信息

Schizophr Res. 2013 May;146(1-3):28-33. doi: 10.1016/j.schres.2013.02.003. Epub 2013 Feb 28.

DOI:10.1016/j.schres.2013.02.003
PMID:23453585
Abstract

Although integrated approaches are recommended and effective for treating patients with co-occurring substance use and psychotic disorders (SUD-PSY), many patients receive standard, nonintegrated substance use disorder (SUD) treatment. Research has yet to investigate how patients with co-occurring substance use and psychotic disorders respond to standard SUD treatment, an issue we address here. In a naturalistic follow-up of 236 male SUD-PSY patients receiving 12-step facilitation or cognitive-behavioral-oriented SUD treatment, we found that patients (1) demonstrated significant improvements in proximal outcomes (e.g., approach coping) from treatment intake to discharge, and in distal outcomes (e.g., psychiatric symptoms, substance use frequency) from treatment intake to 1- and 5-year follow-ups, and (2) tended to have similar outcomes whether they received 12-step facilitation or cognitive-behavioral SUD treatment. Patients who (3) were more involved in treatment, as reflected by more positive perceptions of and more satisfaction, tended to experience better proximal outcomes and engage in more continuing care, and those who (4) experienced better proximal outcomes tended to have better psychiatric and substance use outcomes in the years following treatment. Our results suggest that SUD-PSY patients can benefit from standard SUD treatments, even though it may not directly address their psychiatric disorders.

摘要

尽管综合方法被推荐并对同时患有物质使用障碍和精神障碍(SUD-PSY)的患者有效,但许多患者仍接受标准的、非综合的物质使用障碍(SUD)治疗。目前还没有研究同时患有物质使用障碍和精神障碍的患者对标准 SUD 治疗的反应如何,我们在这里探讨这个问题。在对 236 名接受 12 步促进或认知行为导向的 SUD 治疗的男性 SUD-PSY 患者进行自然随访后,我们发现患者(1)从治疗开始到出院,在近端结果(如应对方式)和从治疗开始到 1 年和 5 年随访时的远端结果(如精神病症状、物质使用频率)上都有显著改善,并且(2)无论接受 12 步促进还是认知行为 SUD 治疗,其结果都趋于相似。(3)对治疗更投入的患者,表现为对治疗的正面看法和更高的满意度,更有可能经历更好的近端结果和接受更多的持续护理,而那些(4)经历更好的近端结果的患者,在治疗后的几年里,精神病和物质使用的结果也更好。我们的结果表明,SUD-PSY 患者可以从标准的 SUD 治疗中受益,尽管这可能无法直接解决他们的精神疾病。

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