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[乳腺癌近距离放射治疗]

[Brachytherapy of breast cancer].

作者信息

Chand M-È, Rivera S, Hennequin C, Hannoun-Lévi J-M, Quero L

机构信息

Département de radiothérapie oncologique, centre Antoine-Lacassagne, 33, avenue de Valombrose, 06189 Nice, France.

出版信息

Cancer Radiother. 2013 Apr;17(2):125-9. doi: 10.1016/j.canrad.2013.01.003. Epub 2013 Feb 27.

Abstract

For breast cancer, interstitial brachytherapy remains an accurate irradiation technique for delivering a high dose (increasing the local control) in a small volume (decreasing the toxicity). In this article, we present the technical data related to the breast brachytherapy proceeding, from the implantation of the vectors to the treatment itself, including the planning. The different indications of breast brachytherapy include all the breast irradiations focusing on the initial tumour bed (partial irradiation of the breast), such as boost, accelerated and partial breast irradiation (APBI) and second conservative radiosurgical treatment in case of ipsilateral in-breast recurrence. The results in terms of efficacy and toxicity are presented for each indication. Interstitial breast brachytherapy, performed according with the standard rules, remains a major technique for breast cancer treatment.

摘要

对于乳腺癌,组织间近距离放射治疗仍然是一种精确的照射技术,可在小体积内给予高剂量照射(提高局部控制率)并降低毒性。在本文中,我们展示了与乳腺近距离放射治疗过程相关的技术数据,从施源器植入到治疗本身,包括治疗计划。乳腺近距离放射治疗的不同适应证包括所有针对初始肿瘤床的乳腺照射(乳腺部分照射),如强化照射、加速乳腺照射和部分乳腺照射(APBI),以及同侧乳腺复发时的二次保乳放射外科治疗。针对每种适应证给出了疗效和毒性方面的结果。按照标准规则进行的组织间乳腺近距离放射治疗仍然是乳腺癌治疗的一项主要技术。

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