Qian K X
Department of Biomedical Engineering, Shanghai Second Medical University, China.
J Biomater Appl. 1990 Apr;4(4):405-18. doi: 10.1177/088532829000400405.
Hemolysis and thrombosis have been considered as the main limitations of the impeller pump and other centrifugal pumps to total heart applications. One of the solutions is to choose the impeller shroud and vane according to the stream surfaces of blood flow, so as to vanish the turbulence and stagnation which cause the hemolysis and thrombosis, respectively, in the pump. This paper describes the method of deducing the stream surfaces together with the velocity distributions in the impeller from the fundamental dynamical equations, and presents a prototype design of the impeller total heart which promises to be an ideal alternative to the problematic diaphragm total heart.
溶血和血栓形成一直被认为是叶轮泵及其他离心泵应用于全人工心脏的主要限制因素。解决方案之一是根据血流的流线面来选择叶轮罩和叶片,从而消除分别导致泵内溶血和血栓形成的湍流和停滞现象。本文描述了从基本动力学方程推导流线面以及叶轮内速度分布的方法,并提出了一种叶轮式全人工心脏的原型设计,有望成为有问题的隔膜式全人工心脏的理想替代品。