Kato S, Fujita T
Department of Anesthesiology and Resuscitation, Gunma University School of Medicine, Maebashi.
Masui. 1990 Mar;39(3):315-9.
The effects of epinephrine infusion on plasma potassium were examined in rats. Potassium infusion (1 mEq.kg-1.h-1 over 2 hours) elevated plasma potassium 4.23 mEq.l-1. Insulin (0.064 U.kg-1.h-1) combined with glucose (0.32 g.kg-1.h-1) or epinephrine (0.05, 0.1, 0.5, 1, or 5 micrograms.kg-1.min-1) added to potassium infusion significantly depressed the increments of plasma potassium levels. Epinephrine infusions (0.05 or 0.1 microgram.kg-1.min-1) were more effective than insulin infusion combined with glucose. These results suggest that epinephrine infusion may be useful for the control of hyperkalemia.
在大鼠中研究了肾上腺素输注对血浆钾的影响。输注钾（2小时内1 mEq·kg⁻¹·h⁻¹）使血浆钾升高4.23 mEq·L⁻¹。在钾输注中加入胰岛素（0.064 U·kg⁻¹·h⁻¹）联合葡萄糖（0.32 g·kg⁻¹·h⁻¹）或肾上腺素（0.05、0.1、0.5、1或5微克·kg⁻¹·min⁻¹）可显著抑制血浆钾水平的升高。肾上腺素输注（0.05或0.1微克·kg⁻¹·min⁻¹）比胰岛素联合葡萄糖输注更有效。这些结果表明，肾上腺素输注可能有助于控制高钾血症。
