Sundram K, Khor H T, Ong A S
Palm Oil Research Institute of Malaysia, Kuala Lumpur.
Lipids. 1990 Apr;25(4):187-93. doi: 10.1007/BF02535746.
Male Sprague Dawley rats were fed semipurified diets containing 20% fat for 15 weeks. The dietary fats were corn oil, soybean oil, palm oil, palm olein and palm stearin. No differences in the body and organ weights of rats fed the various diets were evident. Plasma cholesterol levels of rats fed soybean oil were significantly lower than those of rats fed corn oil, palm oil, palm olein or palm stearin. Significant differences between the plasma cholesterol content of rats fed corn oil and rats fed the three palm oils were not evident. HDL cholesterol was raised in rats fed the three palm oil diets compared to the rats fed either corn oil or soybean oil. The cholesterol-phospholipid molar ratio of rat platelets was not influenced by the dietary fat type. The formation of 6-keto-PGF1 alpha was significantly enhanced in palm oil-fed rats compared to all other dietary treatments. Fatty acid compositional changes in the plasma cholesterol esters and plasma triglycerides were diet regulated with significant differences between rats fed the polyunsaturated corn and soybean oil compared to the three palm oils.
雄性斯普拉格-道利大鼠喂食含20%脂肪的半纯化日粮15周。日粮中的脂肪为玉米油、大豆油、棕榈油、棕榈油精和棕榈硬脂。喂食不同日粮的大鼠的体重和器官重量没有明显差异。喂食大豆油的大鼠的血浆胆固醇水平显著低于喂食玉米油、棕榈油、棕榈油精或棕榈硬脂的大鼠。喂食玉米油的大鼠和喂食三种棕榈油的大鼠的血浆胆固醇含量之间没有明显差异。与喂食玉米油或大豆油的大鼠相比，喂食三种棕榈油日粮的大鼠的高密度脂蛋白胆固醇升高。大鼠血小板的胆固醇-磷脂摩尔比不受日粮脂肪类型的影响。与所有其他日粮处理相比，喂食棕榈油的大鼠中6-酮-前列腺素F1α的形成显著增强。血浆胆固醇酯和血浆甘油三酯中的脂肪酸组成变化受日粮调节，喂食多不饱和玉米油和大豆油的大鼠与三种棕榈油的大鼠之间存在显著差异。
