Department of Otolaryngology, Nishi-Kobe Medical Center, 5-7-1 Koujidai, Nishi-ku, Kobe, Hyogo, 651-2273, Japan,
J Infect Chemother. 2013 Dec;19(6):1158-60. doi: 10.1007/s10156-013-0574-0. Epub 2013 Feb 28.
Today, the opportunity to see tuberculosis is decreasing. Nasopharyngeal tuberculosis is a rare entity, even in endemic tuberculosis areas. A case of nasopharyngeal tuberculosis is described. A 28-year-old woman presented with a sore throat. Irregular mucosal thickening was seen in the nasopharynx. Staining for acid-fast bacilli was positive (Gaffky 1), and the PCR test was positive for Mycobacterium tuberculosis from pharyngeal mucus. Computed tomography showed mucosal thickening in the pharynx and old pulmonary tuberculosis in the right upper lobe. Multiple anti-tuberculosis drug therapy was performed for 6 months. A few days after the initiation of therapy, the pharyngeal pain subsided. The irregular mucosal thickening was quite thin after 1 month of multidrug therapy and was no longer observed after 2 months. A case of nasopharyngeal tuberculosis is reported. A good result was obtained with multiple anti-tuberculous drug therapy for 6 months. Nasopharyngeal tuberculosis should be considered in the differential diagnosis of a white nasopharyngeal coating, especially in a patient with a history of pulmonary tuberculosis.
如今，结核病的就诊机会正在减少。鼻咽结核是一种罕见疾病，即使在结核病流行地区也是如此。本文描述了 1 例鼻咽结核病例。1 例 28 岁女性因咽痛就诊。鼻咽部可见不规则黏膜增厚。抗酸杆菌染色阳性（Gaffky 1），咽拭子聚合酶链反应（PCR）检测结核分枝杆菌阳性。计算机断层扫描（CT）显示咽部黏膜增厚，右上肺陈旧性肺结核。给予患者 6 个月的多种抗结核药物治疗。治疗开始几天后，咽部疼痛缓解。1 个月的多药治疗后，不规则的黏膜增厚变得很薄，2 个月后已观察不到。本文报道了 1 例鼻咽结核病例。患者接受 6 个月的多种抗结核药物治疗后取得了良好的效果。对于白色鼻咽涂层的鉴别诊断，尤其是有肺结核病史的患者，应考虑鼻咽结核。
