Department of Palliative Care, University Hospital Cologne, 50924, Cologne, Germany.
Curr Pain Headache Rep. 2013 Apr;17(4):328. doi: 10.1007/s11916-013-0328-9.
Decades after the publication of the World Health Organization's analgesic ladder, cancer pain is still a major cause of suffering for patients with cancer and affects millions of people worldwide. Owing to the increasing incidence of cancer, cancer-related pain is a major public health problem worldwide. Unfortunately, current research revealed that available options for the successful treatment of cancer pain is still massively underutilized by physicians, and many patients suffer from insufficiently controlled pain despite available treatment options. This review aims to present a concise update about new data or treatment recommendations from the field of cancer pain management. Therefore, information from guidelines, systematic reviews, and original articles that were published in the year 2012 are presented. Specifically, the publication covers information on tapentadol, fixed oxycodone/naloxone combinations, rapid onset fentanyl, nabiximols, ketamine, denusomab, and specialized psychosocial interventions including early palliative care.
世界卫生组织发布止痛阶梯方案几十年后，癌痛仍然是癌症患者的主要痛苦根源，影响着全世界数百万人。由于癌症发病率不断上升，癌痛已成为全球主要的公共卫生问题。遗憾的是，目前的研究显示，尽管有多种治疗选择，但医生对这些选择的应用严重不足，许多患者仍存在疼痛控制不足的情况。本文旨在对癌症疼痛管理领域的新数据或治疗建议进行简要更新。因此，本文介绍了指南、系统评价和 2012 年发表的原始文章中的信息。具体来说，这些出版物涵盖了曲马多、固定剂量羟考酮/纳洛酮复方制剂、快速起效型芬太尼、纳布啡、氯胺酮、地诺单抗以及包括早期姑息治疗在内的专业心理社会干预的信息。
